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AB 4th Year Rheum + Ortho > Rheumatology - VTE Causing > Flashcards

Rheumatology - VTE Causing Flashcards

1
Q

pathology of antiphospholipid syndrome?

A

antiphospholipid antibodies bind to plasma proteins

confirmational change in B2 glycoprotein-1

development of thromboses occurs

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2
Q

features of antiphospholipid syndrome?

A 
recurrent thrombosis
fetal loss
stroke
MI
PE
migraines
athralgia
livedo reticularis
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3
Q

Ix for antiphospholipid syndrome? results?

A

FBC (thrombocytopenia)
U+Es
APTT (falsely prolonged)

lupus anticoagulant
anti cardiolipin Abs
anti beta 2 glycoprotein Abs

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4
Q

Tx for antiphospholipid syndrome?

A

warfarin
heparin if pregnant
aspirin (arterial)

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AB 4th Year Rheum + Ortho (17 decks)

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