Ortho - Bone Disorders + CTD Flashcards
what is osteomalacia?
abnormal bone softening occurring due to lack of Ca and Phosphorous
what is another name for osteomalacia?
Rickett’s
causes of osteomalacia?
malnutrition malabsorption lack of Vit D alcohol CKD anticonvulsants
features of osteomalacia?
bone pain
deformities
path #
what are symptoms of hypocalcaemia?
parasthesia muscle cramps fatigue seizures brittle nails
Ix and results for osteomalacia?
Ca (low)
P (low)
PTH (high)
alk phos (high)
Tx for osteomalacia?
Vit D
Ca + P supplements
what causes paget’s?
increased osteoclast
osteoblasts try to resorp
new poorly modelled bone formed
what type of bone do people with paget’s have?
brittle
thick
misshapen
features of paget’s?
conductive deafness
path #
deformity
pain
Ix and results for paget’s?
Ca and P (normal)
alk phos (raised)
XRAY
DEXA
XRAY features for paget’s?
enlarged bones
thick cortex (lines)
accentuated trabeculae
Tx for paget’s?
bisphosphonates
joint replacement
what gene is affected in marfans? inheritance pattern?
fibrillin
aut dom
features of marfans?
glaucoma high palate pneumothorax pectus excavatum cardiac abnormalities long arms/big hands
