Rheumatology - Vasculitides

Question 1

2 main small vessel?

Answer 1

Non-ANCA

• cutaneous
• IgA vasculitis (Henoch-Schonlein)
• Cryoglobulinemic vasculitis

ANCA associated -

• Granulomatosis(wegner’s)
• Eosinophilic granulomatosis with polyangiitis (churg-Strauss)
• Microscopic polyangiitis

Question 2

Microscopic polyangiitis affects mainly?

Answer 2

Pauci immune necrotizing vasculitis
kidneys
lung

Question 3

Eosinophilic granulomatosis with polyangiitis (churg-Strauss) affects

Answer 3

freq lung
peripheral neuropathy
GI involvement
mycarditis

Question 4

Granulomatosis(wegner’s) affects

Answer 4

resp
kidneys
presents with symptoms of UTI

Question 5

-IgA vasculitis (Henoch-Schonlein) characterisitic?

Answer 5

vacular deposition of IgA

usually in childhood

Question 6

-Cryoglobulinemic vasculitis characteristics?

60-80% are related to which disease

Answer 6

• systemic vasculitis by circulating cryoproteins forming immune complexes
• related to Hep C (60-80%)
• related to Connective tissue disease (5-10%)

Question 7

2 kinds of medium vessel vasculitis?

Answer 7

polyarteritis nodosa

Kawasaki Disease

Question 8

2 large vessel vasculitis?

Answer 8

Giant Cell

Takayasu’s

Question 9

Takayasu’s arteritis

Answer 9

chronic inflammation
aorta and branches
young adults of asian descent

Question 10

2 mimickers of vasculitis?

Answer 10

cholesterol emboli

atrial myxoma

Question 11

2 multi sized vessel vasculitis?

Answer 11

Buerger’s -

Behcet’s

Question 12

what is Buerger’s? what risk? who gets it?

Answer 12

• inflam and clotting in small and medium arteries and veins
• cigarettes
• most common in young asian males

Question 13

what is Behcet’s? presentation? who?

Answer 13

Multi-system presenting with uveitis
oral and genital ulcers
venous thrombosis
skin and joint involvement
mediterranean and asian counties
average age 30 M>F