derm - conditions Flashcards

1
Q

causative agent for impetigo?

A

GAS

S. Aureus

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2
Q

treatment for impetigo?

A

remove crusts
topical antibacterials: mupirocin/fusidic acid
systemic antis, cloxacillin or cephalexin

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3
Q

topical antifungalsfirst line for tinea?

A

clotrimazole
terbinafine
ciclopirox olamine

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4
Q

when antifungal oral therapy?

A

oncomycosis

tinea capitis

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5
Q

what is pemphigus vulgaris etiology?

A

autoimmune

igG produced against epidermal desmoglein 1 and 3

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6
Q

what is pemphigus vulgaris Nikolsky’s sign?

A

shear stress epidermal detachment

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7
Q

where does pemphigus vulgaris 90% happen?

A

mouth then scalp, face, chest etc.

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8
Q

pemphigus vulgaris treatment?

A

pred: 1mg/kg
then
immunosuppressant: aza, cyclo, mycophenolate, ritux, IVIG

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9
Q

Stevens-Johnson syndrome/Toxic epidermal necrolysis affects?

A

skin/mucous membranes

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10
Q

Stevens-Johnson syndrome/Toxic epidermal necrolysis time course

A

1-3 weeks after drug initiation

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11
Q

Stevens-Johnson syndrome/Toxic epidermal necrolysis type of immune response

A

type IV hypersensitivity

T-cell-mediated attacks epithelial and muscosa

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12
Q

Stevens-Johnson syndrome % of body surface?

A

<10%

10-30%

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13
Q

Toxic epidermal necrolysis % TBsA?

A

> 30%

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14
Q

Stevens-Johnson syndrome/Toxic epidermal necrolysis triggers common:

A

carbamazapine
sulfa
immunomodulators
NSAIDS: piroxicam

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15
Q

2 infections that can cause Stevens-Johnson syndrome/Toxic epidermal necrolysis?

A

mycoplasma pneumoniae

CMV

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16
Q

Stevens-Johnson syndrome/Toxic epidermal necrolysis symptoms?

A

fever
flu-like
sloughing

17
Q

Stevens-Johnson syndrome/Toxic epidermal necrolysis diagnosis?

A

punch biopsy

18
Q

Stevens-Johnson syndrome/Toxic epidermal necrolysis treatment?

A

antihistamine
IVIG
steroids

19
Q

Rosacea treatment?

A

AVOID steroids
topical metronidazole
trigger avoidance