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MCCQE1 Jason's > Rheumatology - conditions > Flashcards

Rheumatology - conditions Flashcards

1
Q

what are some seropositive connective tissue diseases?

A 
RA
SLE
antiphospholipid syndrome
scleroderma
polymyositis/dermatomyositis
sjogren's
mixed connective tissue disease
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2
Q

RA definition?

A

chronic
symmetric
erosive synotvitis
peripheral joints

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3
Q

clinical presentation of RA?

A 
symmetrical
morning stiffness >1hour
worse with rest
joint effusion
tenosynovitis
nodules
bone-on bone crepitus
joint deformities
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4
Q

extraarticular features of RA vessels?

A

episcleritis, scleritis

peripheral neuropathy

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5
Q

RA investigations?

A 
increased ESR
decreased platelets
decrease Hb
Rheumatoid factor positive in 80%
anticcp positive in 80%
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6
Q

RA synovial fluid?

A

inflammatory leukocytosis >2000WBC

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7
Q

RA and biologics, multiple?

A

never use two biologics together

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8
Q

mnemonic for SLE?

A 
MD SOAP BRAIN
malar rash
discoid rash
serositis
oral/nasal ulcers
arthritis
photosensitivity
blood
renal disorder
antinuclear antibody
immunologic disorder
neurologic: seizures/psychosis
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9
Q

treatment for SLE?

A

suncreen
NSAIDS
steroids

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10
Q

Scleroderma definition

A

non-inflammatory autoimmune disorder
small vessel vasculopathy, autoantibodies
fibroblast dysfunction causing fibrosis

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11
Q

clinical presentation of scleroderma?

A 
skin tightness
fingers
polyarthralgia
ulcerations finger tips
calcinosis
periungal erythema
raynauds
telangiectasia
gastritis
dysphagia
dyspnoea on exertion
mask-like facies, tight lips,
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12
Q

investigations for scleroderma

A 
ESR up
Hb down
ANA positive
anti-topoisomerase 1
anticentromere
CXR pulmonary fibrosis esophageal
pulmonary function tests for ILD
ECHO for pulmonary htn
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13
Q

what is dermatomyositis?

A

idopathic inflammatory myopathy

proximal skeletal muscle weakness

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14
Q

4 main seronegative arthropathies?

A

ankylosing spondylitis
psoriatic arthritis
reactive arthritis
enteropathic arthritis

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15
Q

Giant cell/temporal arteritis needs 3 of 5 what criteria?

A 
age >50
new headache often temporal
termporal artery tenderness
ESR >50
abnormal artery biopsy
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16
Q

what comorbid condition with giant cell?

A

PMR 30%

17
Q

Giant cell presentation?

A

new temporal headache
scalp tenderness
sudden painless loss of vision
tongue/jaw claudication

18
Q

Polymyalgia Rheumatica definition

A

symmetric proximal pain/stiffness after periods of inactivity (gel phenomenon)
nil muscle weakness

19
Q

Polymyalgia Rheumatica dx criteria?

A

> 50
bilateral shoulder aching
abnormal ESR/CRP

20
Q

Polymyalgia Rheumatica Mx?

A

low dose pred

21
Q

Fibromyalgia management

A 
education
reassurance
exercise program
physical activity
stress reduction
CBY
22
Q

Fibromyalgia diagnostic criteria?

A

> 3/12 non articular pain, tender points

MCCQE1 Jason's (33 decks)

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