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PP clues > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

What is rheumatoid factor?

A

an IgM against IgG Fc

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2
Q

What are tophi?

A

gout crystals + giant cells

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3
Q

What is podagra?

A

big toe inflammaiton

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4
Q

What is CREST syndrome?

A 
C:calcinosis
R: Raynaud's
E: Esophageal dysmotility
S: Sclerodactyly
T: Telangiectasia
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5
Q

What Ab is assoc with CREST?

A

anti-centromere ab

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6
Q

What diseases have Raynaud’s syndrome

A

scleroderma
Takayasu’s
RA
SLE

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7
Q

What platelet count do most types of vasculitides have?

A

low platelets

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8
Q

Which vasculitis has a high platelet count?

A

Kawasaki disease

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9
Q

Which vasculitis has normal platelet count?

A

Henoch-Schonlein Purpura

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10
Q

What is osteoarthritis?

A

pain worse with activity

PIP/DIP joints

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11
Q

What is rheumatoid arthritis?

A

pain worse in morning

MCP/PIP joints

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12
Q

What is Still’s disease?

A

juvenile RA

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13
Q

What is Pseudogout?

A

pyrophosphate crystals in knees and wrists

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14
Q

What is gout?

A

urate crystals in big toe

neg birefringence

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15
Q

What is myositis?

A

1 muscle hurts

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16
Q

What is polymyositis?

A

> 1 muscle weak

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17
Q

What is dermatomyositis?

A

myositis + rash

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18
Q

What is fibromyalgia?

A

hurt all the time

11 trigger points

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19
Q

What is polymyalgia rheumatica?

A

weak shoulders

temporal arteritis

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20
Q

What is SLE (lupus)?

A

discoid rash

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21
Q

What is scleroderma?

A

tight skin

fibrosis

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22
Q

What is Takayasu Arteritis?

A

pulseless Asian women

aorta inflammation

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23
Q

What is Polyarteritis Nodosa?

A

p-ANCA Ab
attacks gut/kidney
Hep B

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24
Q

What is Wegner’s Granulomatosis?

A

c-ANCA Ab

attacks ENT, lungs, kidney

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25
Q

What is Goodpasture’s?

A

anti-GBM ab
attacks lung/kidney
RPGN

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26
Q

What is Reiter’s syndrome?

A

males that can’t see, can’t pee, can’t climb a tree

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27
Q

What is Sjogren’s syndrome?

A

females that have dry eyes/mouth

RA

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28
Q

What is Behcet’s syndrome?

A

oral and genital ulcers

uveitis

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29
Q

What is Churg-Strauss?

A

asthma
eosinohils
multi-organ involvement

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30
Q

What is Felty’s syndrome?

A

RA
leukopeia
spenomegaly

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31
Q

What is Kawasaki’s Disease?

A

CRASH
C: conjunctivitis
R: rash (palms/soles)
A: aneurysm (coronary artery–> MI in kids)
S: strawberry tongue
H: hot (fever >102 for at least 3 days + cervical lymphadenopathy)

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32
Q

What is the complication of temporal ateritis?

A

blindness

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33
Q

What is another name for temporal arteritis?

A

giant cell arteritis

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34
Q

How do you diagnose temporal arteritis?

A

temporal artery biopsy

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35
Q

What is the rule of 60’s for temporal arteritis?

A

age>60
ESR>60
60mg prednisone to tx

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36
Q

What condition is assoc with one muscle hurting?

A

myositis

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37
Q

What condition is assoc with several muscles hurting?

A

polymyositis

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38
Q

What condition is assoc with musle pain plus rash?

A

dermatomyositis

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39
Q

What condition is assoc with inflamed muscle insertions?

A

fibrositis

40
Q

What condition causes pain of muscle and muscle insertion?

A

fibromyalgia

41
Q

What condition is assoc with shoulder girdle hurting most?

A

polymyalgia rheumatica

42
Q

What condition is assoc with visceral cancer?

A

dermatomyositis (colon cancer)

43
Q

What condition is assoc with Rifampin, INH, Statins,Prednisone, and hypothyroidism?

A

myositis

44
Q

What condition is treated with amitriptyline?

A

fibromyalgia

45
Q

What condition is increased in temporal arteritis?

A

polymyalgia rheumatica

46
Q

What condition is assoc with multiple trigger points?

A

fibromyalgia

47
Q

What condition is assoc with muscle pain when moving?

A

fibrositis

48
Q

What condition is assoc with heliotropic rash?

A

dermatomyositis

49
Q

What condition is assoc with a throbbing temporal headache?

A

temporal arteritis

50
Q

What drugs cause myositis?

A

rifampin
INH
statins
prednisone

51
Q

What disease causes myositis?

A

hypothyroidism

52
Q

What is the treatment for multiple sclerosis?

A 
#1 steroids
#2 blocking immunoglobulins (TNF-beta)
#3 plasmapheresis
53
Q

What structure does MS like to attack

A

medial longitudinal fasciculus–> internuclear opthalmoplegia

54
Q

What is the diagnosis for a middle aged woman with optic neuritis (eye problem)?

A

multiple sclerosis

55
Q

What is the equivalent disease to MS in children

A

metachromatic leukodystrophy

56
Q

What vasculitis occurs 2 wks after a common cold?

A

Berger’s

57
Q

What disease presents as a smoking Jew with necrotizing vasculitis?

A

Buerger’s

58
Q

What disease has a family history of deafness and cataracts?

A

Alport’s

59
Q

What vasculitis has a strawberry tongue?

A

Kawasaki’s

60
Q

What vasculitis has fibrin split products?

A

DIC

61
Q

What vasculitis presents 2 wks after E. coli gastroenteritis?

A

hemolytic uremic syndrome

62
Q

What vasculitis presents with fever, thrombocytopenia, and neuro problems?

A

ITP

63
Q

What vasculitis attacks midsize arteries (particularly in GI and kidney)?

A

polyarteritis nodosa

64
Q

What vasculitis affects the sinuses, lung, and kidney

A

Wegner’s Granulomatosis

65
Q

What vasculitis has linear immunofluorescence on GBM with lung involvement?

A

Goodpasture’s

66
Q

What vasculitis has pulmonary infiltrates with eosinophilia?

A

Churg-Strauss

67
Q

What glomerulonephritis occurs two weeks after a sore throat?

A

Post-Strep Glomerulonephritis

68
Q

What vasculitis presents two wks after vaccination?

A

serum sickness

69
Q

What disease leads to septic emboli?

A

subacute bacterial endocarditis

70
Q

What is the only vasculitis with a normal platelet count?

A

HSP

71
Q

What is the only vasculitis with a high platelet count?

A

Kawasaki’s

72
Q

What is the MCC of death in SLE?

A

renal failure

73
Q

What protein is decreased in all vasculitides?

A

haptoglobin

74
Q

What cellular response is seen in all vasculitides?

A

T cells and macrophages

75
Q

What are the clues for Kawasaki?

A

mucositis
rash on palms and soles
cervical lymph nodes
fever>102 for >3days

76
Q

What are the clues for TTP?

A

fever
thrombocytopenia
neurologic problems

77
Q

What are the clues for polyarteritis nodosa?

A

midsized arteries (GI and renal)
associated with Hep B
p-ANCA

78
Q

What are the clues for Churg-Strauss?

A

allergic vasculitis

79
Q

What are the clues for SBE?

A

caused by strep viridens

80
Q

What are the clues for MPGN I?

A

tram tracks with C3 nephritic factor in basement membrane

81
Q

What are the clues for MPGN II?

A

tram tracks with low complement (dense deposit disease)

82
Q

What are clues for CREST?

A

mildest form of scleroderma

patchy involvement

83
Q

What are the clues for scleroderma?

A

anti-scl70 Ab

anti-sm muscle Ab

84
Q

What are clues for progressive systemic sclerosis?

A

scleroderma with organ involvement

85
Q

What are clues for rheumatoid arthritis?

A

symmetrical polyarteritis

worse in morning

86
Q

What are clues for juvenile rheumatoid arthritis?

A

arthritis with iridesis

87
Q

What are clues for Felty’s?

A

RA + leukopenia + splenomegaly

88
Q

What are clues for Behcet’s?

A

RA + GI ulcers

89
Q

What are clues for Sjogren’s?

A

RA + dry eyes, dry mouth

90
Q

What is the vasculitis with GI bleeding, intussusception, and normal platelet count?

A

HSP

91
Q

What is the vasculitis whose most common cause of sepsis?

A

DIC

92
Q

What is the most common cause of renal failure in children?

A

HUS

93
Q

What is the vasculitis with which Hep B is assoc with?

A

PAN

94
Q

What vasculitis causes pulmonary infiltrate with eosinophilia?

A

Churg-Strauss

95
Q

What vasculitis has xerophthalmia and xerostomia?

A

sjogren’s

96
Q

What is the most common cause of arthritis in a middle aged female?

A

rheumatoid arthritis

97
Q

What is the only arthritis that attacks the synovium?

A

rheumatoid arthritis

PP clues (13 decks)

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