Rheumatology 2 Flashcards
what disease is known as “the disease of 1000 faces”
systemic lupus erythematosus
what is the women:men ratio for lupus?
9:1
Systemic autoimmune disorder characterized by a number of auto-antibodies-specifically antibodies against ?
nuclear components (ANA)
what are the ANAs specific to SLE?
- anti-ds DNA
- anti-smith antigen antibodies
what’s discoid lupus?
skin manifestations of lupus with few to no systemic symptoms
Seronegative spondyloarthropathies are a group of disorders characterized by?
- lack of serum markers
- association with HLA-B27
- inflammation of synovial joints
what are the disorders under seronegative spondyloarthropathies?
- ankylosing spondylitis
- reactive arthritis
- psoriatic arthritis
- arthritis associated with IBD
what does ankylosing mean?
fusion of a joint
what does spondylitis mean?
inflammation of the intervertebral joints
what is the most common of the spondyloarthropathies
ankylosing spondylitis
what is enthesitis?
commonly at site of achilles tendon insertion, inflammatory joint pain that is typically moderate-severe
what are the two types of reactive arthritis?
post-urethritis and enteritis-associated arthritis
what is enteritis-associated arthritis?
arthritis that occurs after a gastrointestinal infection
what can result in significant destruction and deformity of a digit?
dactylitis
