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MRCP Part 1 > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

Oral Ulcer + Genital Ulcer + Anterior Uveitis

A

Bechets Disease

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2
Q

Early Morning stiffness in hip and shoulder + Polyclonal increase in gammaglobulins

A

Polymyalgia Rheumatica

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3
Q

Preiser’s Disease

A

Bilateral Avascular necrosis of Scaphoid Bone

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4
Q

Fever + Swollen DIP + Transient Rash + Hepatosplenomegaly

A

Still’s Disease

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5
Q

Headache + Vertigo + claudication pain + weak pulse

A

Takayasu’s Arteritis

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6
Q

Symmetrical Proximal Muscle weakness + Increased Creatine Kinase

A

Polymyositis

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7
Q

Pulse in arm disappear when arm is raised above head

A

Thoracic Outlet Syndrome

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8
Q

Anti-CCP Antibody positive seen in

A

Rheumatoid Arthritis

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9
Q

Anti Ro Antibody positive seen in

A

Sjogren Syndrome

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10
Q

Anti Scl-70 antibody positivity seen in

A

Diffuse Systemic Sclerosis

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11
Q

Complement Deficiency associated with SLE

A

C4

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12
Q

Anti ds-DNA positive seen in

A

SLE

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13
Q

Anti-centeromere antibody positive seen in

A

Limited Systemic Sclerosis

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14
Q

Anti histone antibody seen in

A

Drug Induced Lupus

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15
Q

Raised CRP and ESR + Polymorphonuclear leucocytosis

A

Polyarteritis Nodosa

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16
Q

Rheumatoid arthritis features but nail features also present

A

Psoriatic Arthritis

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17
Q

DEXA Score for Osteopenia and Osteoporosis

A

-1 to -2.5 is Osteopenia
More than -2.5 is osteoporosis

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18
Q

Sickle Cell Disease with Hip pain shows loss of femoral head

A

Avascular Necrosis

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19
Q

Long term corticosteroids use now complaints of hip pain

A

Avascular Necrosis

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20
Q

muscle pain + violet or purple rash in cheeks with normal CRP and ESR

A

Dermatomyositis

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21
Q

Earliest evidence of Rheumatoid Arthritis of Knee

A

Knee Effusion

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22
Q

Ankylosing Spondylitis DOC

A

Etanercept

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23
Q

Polymyositis + Lung Fibrosis + Rhabdomyolysis

A

Anti jo 1 Syndrome

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24
Q

Joint complication of hemochromatosis

A

Pseudo-gout

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25
Q

Pain and paresthesia by applying pressure on medial malleolus

A

Tarsal Tunnel Syndrome - Tibial Nerve

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26
Q

Isolated elevated ALP Seen in

A

Paget’s Disease

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27
Q

Gout management in Congestive heart disease and CKD

A

Colchicine

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28
Q

HLA B-27 positive Ankylosing Spondylitis biological agent used

A

Adalimumab

29
Q

Peau de orange appreance + bilateral carpel tunnel syndrome + eosinophilia

A

Eosinophilic Fasciitis

30
Q

Polymyositis best diagnostic investigation

A

Muscle Biopsy

31
Q

Herberden Nodes seen in

A

Osteoarthritis

32
Q

Immunoglobulin commonly detected by routine testing in Rheumatoid Arthritis

A

IgM

33
Q

Antibody most associated with complete heart block of newborn and neonatal lupus

A

Anti-Ro

34
Q

Bloody Diarrhoea + Erythema nodosum + painful knee

A

Enteropathic Arthritis

35
Q

Safest Anti Rheumatic drug for pregnancy

A

Hydroxychloroquine

36
Q

Type of Ischemic Neuropathy in Giant Cell Arteritis

A

Anterior Ischemic Optic Neuropathy

37
Q

Calcification of articular cartilage or meniscus

A

Pyrophosphate Arthropathy

38
Q

Treatment of Gout

A

Acute attack - Colchicine
Prevent - Allopurinol

39
Q

Interleukin Involved in Rheumatoid Arthritis

A

IL-6

40
Q

Active movement of shoulder is limited but passive movement is present

A

Supraspinatus tendonitis

41
Q

Both Active and Passive movements are affected

A

Adhesive Capsulitis

42
Q

Felty Syndrome triad

A

Splenomegaly + Rheumatoid Arthritis + Neutropenia

43
Q

Osteoporosis in DEXA how to manage based on GFR

A

GFR >35 - Alendronic Acid
GFR <35 - Denosumab

44
Q

Anti gout medication causing increase in Didanosine concentration

A

Allopurinol

45
Q

Physical examination test suggestive of Ankylosing Spondylitis

A

Positive Schober’s Test

46
Q

Earliest Clinical Sign of Ankylosing Spondylitis

A

Retention of lumbar lordosis during spinal flexion

47
Q

Previous joint injury that was treated now complaints of severe pain but no Findings

A

Reflex Sympathetic Dystrophy

48
Q

Marked Vascular Proliferation in synovial membrane seen in

A

Rheumatoid Arhtritis

49
Q

Anti tubercular drug causing gout

A

Pyrazinamide

50
Q

Patient on Adalimumab complaints of cough, weightloss and night sweats

A

Reactivation of Tuberculosis

51
Q

TNF alpha associated with

A

Rheumatoid Arthritis

52
Q

Mesenteric Vasculitis seen in

A

Polyarteritis Nodosa

53
Q

Most common site affected in Pagets disease of bone

A

Lumbar spine

54
Q

Pagets disease management

A

IV Zoledronate

55
Q

APLA Antibody responsible for miscarriage

A

Anti beta 2 glycoprotein 1

56
Q

Joint aspiration shows rhomboid crystals

A

Pyrophosphate Arthritis

57
Q

Lateral Hip and Thigh pain worse on direct pressure

A

Trochanteric Bursitis

58
Q

Antibody associated with Mixed Connective Tissue Disease

A

Anti- Ribonucleoprotein antibody

59
Q

Hypertelorism + Tetany + Absent Thymus

A

Di George Syndrome

60
Q

Thalidomide side effect

A

Peripheral Neuropathy

61
Q

Food Allergy testing investigation of choice

A

Skin Prick Testing

62
Q

Investigation for Paroxysmal Nocturnal Hemoglobinuria

A

CD 59 and CD 55 assay

63
Q

APLA Common antibody

A

Anti Beta 2 glycoprotein antibody

64
Q

Antibody associated with Paraneoplastic cerebellar syndrome

A

Anti-Yo

65
Q

Pain and swelling over tibial tubercle + seen in young athletes

A

Osgood Schlatters Disease

66
Q

Long term medication of choice for Rheumatoid Arthritis

A

Methotrexate

67
Q

Most important risk factor for Osteonecrosis of jaw in bisphosphonate treatment

A

Dental Caries

68
Q

Initial management of Knee Osteoarthritis

A

Swimming

MRCP Part 1 (17 decks)

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