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MRCP Part 1 > Gastroenterolgy and Hepatology > Flashcards

Gastroenterolgy and Hepatology Flashcards

1
Q

On Treatment of Whipple’s Disease + Diarrhea + Joint Pain

A

Immune reconstitution inflammatory syndrome

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2
Q

Ferritin Deficiency + Folate Deficiency + Diarrhoea

A

Coeliac Disease

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3
Q

Indication of Anti HBc IgM +

A

Acute Infection

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4
Q

Indication of Anti HBc IgG +

A

Past Infection

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5
Q

Anti HBs + but Anti HBc -ve

A

Vaccination

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6
Q

Anti HBc IgG +ve and IgM Anti delta

A

Hepatitis D infection

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7
Q

Drugs Causing Cholestasis

A
  1. Oestrogens
  2. Haloperidol
  3. Erythromycin
  4. Nitrofurantoin
  5. Ibuprofen
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8
Q

Drugs Causing Acute Hepatitis

A
  1. Isoniazid
  2. Rifampicin
  3. Amiodarone
  4. Ketoconazole
  5. Atenolol
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9
Q

Rotor syndrome features

A

Conjugated Hyperbilirubinemia and Normal liver histology

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10
Q

Dubin Johnson features

A

Conjugated hyperbilirubinemia and granular hepatic pigmentation in liver histology

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11
Q

Primary Sclerosing Cholangitis Antibody

A

ANCA

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12
Q

Primary Biliary Cirrhosis Antibody

A

AMA

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13
Q

Management of Achalasia Cardia

A

Balloon Dialation of Esophagus

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14
Q

Type of Colonic Polyp with worst prognosis

A

Serrated Polyp

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15
Q

Predisposing factors for Gallstone formation

A

3 C Female
1. Female
2. OCP
3. Cirrhosis
4. Crohns Disease
5. Ileal Resection

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16
Q

Increased Risk Factors for Cirrhosis

A
  1. Alpha one Antitrypsin deficiency
  2. Primary Hemochromatosis
  3. Aflatoxin
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17
Q

Mucosa Associated Lymphoid Tissue (MALT) Lymphoma most common Association

A

H.pylori

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18
Q

Cause of Lipaemic blood sample in Acute Pancreatitis

A

Chylomicrons

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19
Q

Refeeding Syndrome which electrolyte imbalance

A

Phosphate

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20
Q

Hepatits C with Rash on leg and joint pain

A

Mixed or Type II Cryoglobulinaemia

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21
Q

Antibody for Autoimmune Hepatitis

A

Smooth Muscle Antibodies

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22
Q

Type of gallstone in sickle cell, hereditary spherocytosis and thalassemia

A

Black Pigment stone

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23
Q

pANCA Positive and Bloody Diarrhea

A

Ulcerative Colitis

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24
Q

Diagnosis of Liver Biopsy showing Ground Glass hepatocytes

A

Chronic HBV

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25
Q

Diagnosis of Liver Biopsy showing Lymphoid Aggregates

A

Hepatitis C infection

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26
Q

Diagnosis of Liver Biopsy showing marked cholestasis

A

Hepatitis E

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27
Q

Diagnosis of Liver Biopsy showing Microvesicular Steatosis

A

Hepatitis D

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28
Q

Crohns Disease with Ileal resection with watery diarrhea diagnosis and management

A

Bile Salt malabsorption
Management - Cholestyramine

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29
Q

OGD shows gastric folds and HPE shows hyperplasia of gastric pits and increased mucosal thickness

A

Menetrier’s Disease

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30
Q

Esophageal Variceal bleed first line management

A

Band Ligation

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31
Q

Gastric Varices first line management

A

Sclerotherapy

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32
Q

Most common side effect of Ribavirin

A

Haemolytic Anemia

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33
Q

Parkinsons disease with episodes of bloating and abdominal distention which resolves spontaneously

A

Intestinal Pseudo-Obstruction

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34
Q

Confirmation of H.pylori eradication

A

Urea breath test

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35
Q

Test to assess function of pancreas in Chronic Pancreatitis

A

Fecal Elastase

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36
Q

SeHCAT test Indication

A

Test for Bile Acid Absorption

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37
Q

Drug causing SeHCAT test +ve

38
Q

Specific Blood Test for Upper GI bleed

A

Urea or Urea :Creatinine ratio

39
Q

IOC for Perianal abscess

A

MRI pelvis

40
Q

Macrocytic Anemia + Hypocalcemia + Stay in Tropical Region

A

Tropical Sprue

41
Q

Coeliac Disease antibodies

A
  • tissue transglutaminase IgA
  • endomysial antibodies
  • anti-gliadin antibodies
42
Q

Whipple’s disease HPE Finding

A

“foamy macrophages” with PAS Positive

43
Q

Investigation of Choice for Diagnosing Gastroparesis

A

Gamma Scintigraphy

44
Q

Management of Diabetic Gastroparesis

A

Domperidone

45
Q

Genes of Coeliac Disease

A

HLA-DQ2 and HLA-DQ8

46
Q

Poultry or Egg or Milk + Blood Diarrhoea

A

Salmonella

47
Q

Pre Made food + Soon after Eating (2-4 Hours)

A

Staphylococcal

48
Q

Investigations for Carcinoid Tumors

A
  • urinary 5-HIAA
  • Plasma chromogranin A
49
Q

Increased Stool Leukocytes Seen in

A

Entamoeba Histolytica

50
Q

Release of Gastrin in triggered by

A

Gastrointestinal Luminal Peptides

51
Q

Severe Malnutrition Complication in Liver

A

Steatohepatitis

52
Q

Malignancy Associated with Primary Sclerosing Cholangitis

A

Cholangiocarcinoma

53
Q

Pruritus + Elevated Bile acids in second or third trimester

A

Intrahepatic Cholestasis of Pregnancy

54
Q

Deranged LFT + Hypoglycaemia + Thrombocytopenia in third trimester

A

Acute Fatty Liver of Pregnancy

55
Q

Diabetic Symptoms + Liver Disease Symptoms

A

Hemochromatosis

56
Q

Anti LKM Antibody associated with

A

Drug Induced Hepatitis

57
Q

Side Effect of Azathioprine

A

Pancreatitis

58
Q

Dysphagia to Solids and Liquids + Regurgitation which relieve symptoms of fullness

A

Achalasia Cardia

59
Q

Most Indicative Sign of Advanced Portal Hypertension

A

Caput Medusa

60
Q

Protein C Deficiency + Previous Surgery Scar now with diarrhoea

A

Short Bowel Syndrome

61
Q

Partial Thromboplastin Time (PPT) not improving on 50:50 Mixing

62
Q

Lactose Intolerance after Loose Stools + Outside food

A

Giardiasis

63
Q

Test to be done before starting Azathioprine

A

TPMT Enzyme Test

64
Q

Abetaliproteinemia causes elevation of which blood parameter

A

Prothrombin Time (Decreased absorption of Vitamin K)

65
Q

Howell-Jolly Body Seen in

A

Hyposplenism

66
Q

Hemochromatosis Gene Responsible

67
Q

Crohn’s Like CF + Fecal Calprotectin + but is on Mycophenolate Mofetil

A

Mycophenolate Mofetil induced enterocolitis

68
Q

H.pylori increased risk of which cancer

A

Gastric B-Cell Lymphoma

69
Q

Post Cholecystectomy complaints of diarrhoea cause

A

Bile Acid Diarrhoea

70
Q

Antibiotic Of Choice in SBP

A

IV Ceftriaxone

71
Q

Most important differentiating factor for IBS and Ca Colon

A

Nocturnal Diarrhoea

72
Q

Typhoid Disease method to confirm chronic carrier state

A

culture of intestinal secretions

73
Q

Down Syndrome + Constipation + Acute Abdominal Pain

A

Meckels Diverticulum

74
Q

Anti-emetic safest in parkinsons disease

75
Q

Isolated Hypertriglyceridemia seen in

A

Alcoholics

76
Q

Cholera Toxin site of Action

A

GM-1 Receptor Agonist

77
Q

Cause for Metabolic Alkalosis in Cirrhosis

A

Relative Intravascular volume depletion

78
Q

Gilbert Syndrome diagnose clinically

A

Absence of Bilirubin in Urine

79
Q

Fluid of choice for paralytic ileus with NT Tube draining

A

0.9% NaCl with K+

80
Q

Patient with Ileostomy with low calcium

A

Hypomagnesemia due to loss thro ileostomy

81
Q

Imatinib use other than Philadelphia positive CML

82
Q

GLUT Responsible for absorption from intestine

83
Q

Intrinsic factor produced by which part of stomach

A

Fundus of Stomach

84
Q

Females with HNPCC have increased risk of which cancer

A

Endometrial Cancer

85
Q

Gastrointestinal Stromal Tumor why use Imatinib

A

Block Kit (c-kit)

86
Q

FAP with multiple polyps of high grade dysplasia management

A

Proctocolectomy with ileal pouch-anal anastomosis

87
Q

Watershed Area in colon most vulnerable to Ischemia

A

Splenic Flexure

88
Q

Management of mild to moderate proctitis in UC

A

Rectal Mesalamine

89
Q

Investigation to confirm Entamoeba histolytica

A

Hot stool (stool sample sent within 15 mins to local lab)

90
Q

Elderly + bleeding + Iron deficiency anaemia but NOT Cancer

A

Angiodysplasia

91
Q

Murmur Associated with AngiodySplasia

A

Aortic Stenosis (A and S in both words)

92
Q

Chronic anal fissure management

A

Topical GTN ointment for 6-8 weeks

MRCP Part 1 (17 decks)

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