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MRCP Part 1 > Gastroenterolgy and Hepatology > Flashcards

Gastroenterolgy and Hepatology Flashcards

1
Q

On Treatment of Whipple’s Disease + Diarrhea + Joint Pain

A

Immune reconstitution inflammatory syndrome

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2
Q

Ferritin Deficiency + Folate Deficiency + Diarrhoea

A

Coeliac Disease

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3
Q

Indication of Anti HBc IgM +

A

Acute Infection

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4
Q

Indication of Anti HBc IgG +

A

Past Infection

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5
Q

Anti HBs + but Anti HBc -ve

A

Vaccination

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6
Q

Anti HBc IgG +ve and IgM Anti delta

A

Hepatitis D infection

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7
Q

Drugs Causing Cholestasis

A
  1. Oestrogens
  2. Haloperidol
  3. Erythromycin
  4. Nitrofurantoin
  5. Ibuprofen
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8
Q

Drugs Causing Acute Hepatitis

A
  1. Isoniazid
  2. Rifampicin
  3. Amiodarone
  4. Ketoconazole
  5. Atenolol
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9
Q

Rotor syndrome features

A

Conjugated Hyperbilirubinemia and Normal liver histology

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10
Q

Dubin Johnson features

A

Conjugated hyperbilirubinemia and granular hepatic pigmentation in liver histology

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11
Q

Primary Sclerosing Cholangitis Antibody

A

ANCA

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12
Q

Primary Biliary Cirrhosis Antibody

A

AMA

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13
Q

Management of Achalasia Cardia

A

Balloon Dialation of Esophagus

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14
Q

Type of Colonic Polyp with worst prognosis

A

Serrated Polyp

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15
Q

Predisposing factors for Gallstone formation

A

3 C Female
1. Female
2. OCP
3. Cirrhosis
4. Crohns Disease
5. Ileal Resection

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16
Q

Increased Risk Factors for Cirrhosis

A
  1. Alpha one Antitrypsin deficiency
  2. Primary Hemochromatosis
  3. Aflatoxin
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17
Q

Mucosa Associated Lymphoid Tissue (MALT) Lymphoma most common Association

A

H.pylori

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18
Q

Cause of Lipaemic blood sample in Acute Pancreatitis

A

Chylomicrons

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19
Q

Refeeding Syndrome which electrolyte imbalance

A

Phosphate

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20
Q

Hepatits C with Rash on leg and joint pain

A

Mixed or Type II Cryoglobulinaemia

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21
Q

Antibody for Autoimmune Hepatitis

A

Smooth Muscle Antibodies

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22
Q

Type of gallstone in sickle cell, hereditary spherocytosis and thalassemia

A

Black Pigment stone

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23
Q

pANCA Positive and Bloody Diarrhea

A

Ulcerative Colitis

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24
Q

Diagnosis of Liver Biopsy showing Ground Glass hepatocytes

A

Chronic HBV

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25
Diagnosis of Liver Biopsy showing Lymphoid Aggregates
Hepatitis C infection
26
Diagnosis of Liver Biopsy showing marked cholestasis
Hepatitis E
27
Diagnosis of Liver Biopsy showing Microvesicular Steatosis
Hepatitis D
28
Crohns Disease with Ileal resection with watery diarrhea diagnosis and management
Bile Salt malabsorption Management - Cholestyramine
29
OGD shows gastric folds and HPE shows hyperplasia of gastric pits and increased mucosal thickness
Menetrier's Disease
30
Esophageal Variceal bleed first line management
Band Ligation
31
Gastric Varices first line management
Sclerotherapy
32
Most common side effect of Ribavirin
Haemolytic Anemia
33
Parkinsons disease with episodes of bloating and abdominal distention which resolves spontaneously
Intestinal Pseudo-Obstruction
34
Confirmation of H.pylori eradication
Urea breath test
35
Test to assess function of pancreas in Chronic Pancreatitis
Fecal Elastase
36
SeHCAT test Indication
Test for Bile Acid Absorption
37
Drug causing SeHCAT test +ve
Metformin
38
Specific Blood Test for Upper GI bleed
Urea or Urea :Creatinine ratio
39
IOC for Perianal abscess
MRI pelvis
40
Macrocytic Anemia + Hypocalcemia + Stay in Tropical Region
Tropical Sprue
41
Coeliac Disease antibodies
- tissue transglutaminase IgA - endomysial antibodies - anti-gliadin antibodies
42
Whipple's disease HPE Finding
"foamy macrophages” with PAS Positive
43
Investigation of Choice for Diagnosing Gastroparesis
Gamma Scintigraphy
44
Management of Diabetic Gastroparesis
Domperidone
45
Genes of Coeliac Disease
HLA-DQ2 and HLA-DQ8
46
Poultry or Egg or Milk + Blood Diarrhoea
Salmonella
47
Pre Made food + Soon after Eating (2-4 Hours)
Staphylococcal
48
Investigations for Carcinoid Tumors
- urinary 5-HIAA - Plasma chromogranin A
49
Increased Stool Leukocytes Seen in
Entamoeba Histolytica
50
Release of Gastrin in triggered by
Gastrointestinal Luminal Peptides
51
Severe Malnutrition Complication in Liver
Steatohepatitis
52
Malignancy Associated with Primary Sclerosing Cholangitis
Cholangiocarcinoma
53
Pruritus + Elevated Bile acids in second or third trimester
Intrahepatic Cholestasis of Pregnancy
54
Deranged LFT + Hypoglycaemia + Thrombocytopenia in third trimester
Acute Fatty Liver of Pregnancy
55
Diabetic Symptoms + Liver Disease Symptoms
Hemochromatosis
56
Anti LKM Antibody associated with
Drug Induced Hepatitis
57
Side Effect of Azathioprine
Pancreatitis
58
Dysphagia to Solids and Liquids + Regurgitation which relieve symptoms of fullness
Achalasia Cardia
59
Most Indicative Sign of Advanced Portal Hypertension
Caput Medusa
60
Protein C Deficiency + Previous Surgery Scar now with diarrhoea
Short Bowel Syndrome
61
Partial Thromboplastin Time (PPT) not improving on 50:50 Mixing
Phenytoin
62
Lactose Intolerance after Loose Stools + Outside food
Giardiasis
63
Test to be done before starting Azathioprine
TPMT Enzyme Test
64
Abetaliproteinemia causes elevation of which blood parameter
Prothrombin Time (Decreased absorption of Vitamin K)
65
Howell-Jolly Body Seen in
Hyposplenism
66
Hemochromatosis Gene Responsible
C282Y
67
Crohn's Like CF + Fecal Calprotectin + but is on Mycophenolate Mofetil
Mycophenolate Mofetil induced enterocolitis
68
H.pylori increased risk of which cancer
Gastric B-Cell Lymphoma
69
Post Cholecystectomy complaints of diarrhoea cause
Bile Acid Diarrhoea
70
Antibiotic Of Choice in SBP
IV Ceftriaxone
71
Most important differentiating factor for IBS and Ca Colon
Nocturnal Diarrhoea
72
Typhoid Disease method to confirm chronic carrier state
culture of intestinal secretions
73
Down Syndrome + Constipation + Acute Abdominal Pain
Meckels Diverticulum
74
Anti-emetic safest in parkinsons disease
Cyclizine
75
Isolated Hypertriglyceridemia seen in
Alcoholics
76
Cholera Toxin site of Action
GM-1 Receptor Agonist
77
Cause for Metabolic Alkalosis in Cirrhosis
Relative Intravascular volume depletion
78
Gilbert Syndrome diagnose clinically
Absence of Bilirubin in Urine
79
Fluid of choice for paralytic ileus with NT Tube draining
0.9% NaCl with K+
80
Patient with Ileostomy with low calcium
Hypomagnesemia due to loss thro ileostomy
81
Imatinib use other than Philadelphia positive CML
GIST
82
GLUT Responsible for absorption from intestine
GLUT-2
83
Intrinsic factor produced by which part of stomach
Fundus of Stomach
84
Females with HNPCC have increased risk of which cancer
Endometrial Cancer
85
Gastrointestinal Stromal Tumor why use Imatinib
Block Kit (c-kit)
86
FAP with multiple polyps of high grade dysplasia management
Proctocolectomy with ileal pouch-anal anastomosis
87
Watershed Area in colon most vulnerable to Ischemia
Splenic Flexure
88
Management of mild to moderate proctitis in UC
Rectal Mesalamine
89
Investigation to confirm Entamoeba histolytica
Hot stool (stool sample sent within 15 mins to local lab)
90
Elderly + bleeding + Iron deficiency anaemia but NOT Cancer
Angiodysplasia
91
Murmur Associated with AngiodySplasia
Aortic Stenosis (A and S in both words)
92
Chronic anal fissure management
Topical GTN ointment for 6-8 weeks

MRCP Part 1 (17 decks)

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