Neurology Flashcards

1
Q

Herpes Simplex Encephalitis Management

A

IV Fluids and Acyclovir

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2
Q

Roth Spots on Retina + Headaches + Decreased Consciousness

A

Carbon Monoxide Poisoning

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3
Q

Weakness Increases with Activity

A

Myasthenia Gravis

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4
Q

Weakness decreases with Activity

A

Lambert-Eaton Myasthenic Syndrome (LEMS)

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5
Q

Anti-GM1 antibody associated with

A
  1. Guillain-Barré syndrome
  2. Multifocal Motor Neuropathy
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6
Q

Anti-GQ1b Antibody associated with

A

Miller Fischer Syndrome

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7
Q

Post Partum + Seizures + Papilloedema

A

Cerebral Venous Thrombosis

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8
Q

Meningitis with Brainstem involvement

A

Listeria

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9
Q

Meningitis seen in elderly, diabetics and alcoholics

A

Listeria

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10
Q

Lymphocyte Predominant Meningitis

A
  1. Nocardia
  2. Mycobacterium
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11
Q

Unilateral Hearing loss + Tinnitus + Trigeminal Neuropathy

A

Vestibular Schwanoma

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12
Q

NICE Recommendation for preventing secondary Cerebral infarction

A

Clopidogrel

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13
Q

Teenager + Early Morning Seizures + Myoclonic Jerks

A

Juvenile Myoclonic Epilepsy

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13
Q

Management of Torticollis

A

Botox Injection

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14
Q

Juvenile Myoclonic Epilepsy Management

A

Levetiracetam

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14
Q

Facial Weakness + Winged Scapula + Elevated CK

A

Facioscapulohumeral Muscular Dystrophy

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15
Q

Normal Creatine Kinase + Muscle Weakness in Quadriceps

A

Inclusion body Myositis

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15
Q

Neurogenic Detrusor activity management

A
  • PRV <100 → Oxybutinin
  • PRV >100 → Intermittent self catheterization
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16
Q

Unable to Walk due to weakness but Cycling can be done

A

Lumbar Canal Stenosis

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16
Q

Anti Tubercular medication causing sensory neuropathy

A

Isoniazid

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17
Q

Fingolimod Mechanism of Action

A

Sphingosine 1 Phosphate receptor modulator

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17
Q

MRI Finding of Subacute Combined Degeneration of spinal cord

A

Increased T-2 Weighted signal in the posterior column

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18
Q

Management of Essential Tremors

A

Propranolol or Topiramate

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18
Q

Inferior quadrantanopia caused by

A

a lesion in the parietal lobe (Opposite side)

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19
Superior quadrantanopia caused by
a lesion in the temporal lobe (Opposite side)
20
Management of Tourette Syndrome
Risperidone
21
Hypodense areas in both temporal lobes seen in MRI
Herpes Simplex Encephalitis
22
Trigeminal Neuralgia Management
Carbamazepine
23
Raised CSF proteins (Albumino-cytological dissociation)
Gullian-Bare Syndrome
24
Oligoclonal bands seen in
Multiple Sclerosis
25
Raised Lactate in CSF seen in
Mitochondrial Encephalopathy with Lactic Acidosis
26
Nerve affected in Foot Drop
Common Peroneal Nerve
27
Nerve affected in Weakness of Knee Extension and Hip Flexion
Femoral Nerve
28
Nerve affected in weakness of Hip adduction
Obturator Nerve
29
Changes in Personality and Behaviors but no memory defect
Fronto-Temporal Dementia
30
Seizure + epigastric aura + fear + lip smacking
Temporal Lobe Epilepsy
31
Seizure + vertigo + hallucinations
Parietal Lobe Epilepsy
32
LMN signs in arms + UMN signs in legs
Motor Neuron Disease
33
EMG Finding in Motor Neuron Disease
Reduced number of action potentials with increased amplitude.
34
EMG Shows - Dive bomber effect" (waxing and waning potentials).
Myotonic Dystrophy
35
EMG Finding in Polymyositis and Dermatomyositis
Small short-duration motor unit potentials.
36
Specific Area for Hemiballism
Subthalamic Nucleus of Basal Ganglia
37
Specific Area for Huntingtons
Caudate Nucleus of Basal Ganglia
38
Commonest Causes of Young Onset Stroke
1. Carotid Artery Dissection 2. Cardio Embolism
39
Triad of Carotid Artery Dissection
1. Unilateral Headache 2. Ipsilateral Horners Syndrome 3. Contralateral Visual Disturbance
40
Migraine + Recurrent Ischaemic Events
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)
41
Gene for CADASIL
Chromosome 19 NOTCH 3
42
Wernicke's Aphasia Site of Lesion
Superior Temporal Gyrus
43
Brocas Aphasia Site of Lesion
Inferior Frontal Gyrus
44
Brown-Séquard Syndrome Mnemonic
I LOST PALS I → Ipsilateral: LO → Loss of proprioception and vibration. S → Spastic paralysis T → Loss of fine touch. Contralateral PALS → Pain And Loss of temperature
45
Wasting and Weakness of Hand + Loss of Pain and Temperature
Syringomyelia
46
Ptosis + Miosis
Horners Syndrome
47
Ptosis + Mydriasis
3rd Nerve Palsy
48
Headache + 3rd Never palsy + Dilated Pupil
PCA Aneurysm
49
3rd Never palsy sparing the pupil
Ischemic Oculomotor Palsy
50
Frontal Lobe Epilepsy features
Post Ictal weakness + Jacksonian march
51
Temporal Lobe Epilepsy features
Hallucination Epigastric Rising Automatism
52
GBS respiratory assessment marker
Vital Capacity
53
Anisocoria more evident in Light than dark seen in
Holmes-Adie Syndrome
54
Anisocoria + Loss of Deep Tendon Reflex
Holmes-Adie Syndrome
55
Arnold-Chiari Malformation type of Nystagmus seen
Downbeat
56
Palpable Nodule + Seizures Diagnosis
Cysticercosis
57
Test for confirming brainstem death
Oculi-vestibular reflex
58
Acoustic Neuroma + Unilateral Hearing loss effects which other nerve
Trigeminal - Loss of Corneal Reflex
59
Psychiatric Symptoms + Myoclonic Jerk + Rapidly progressive dementia
Creutzfeldt-Jakob disease
60
Young + Hypokalemia + paralysis
Periodic Paralysis
61
Ophthalmoplegia + Ataxia + Areflexia
Miller Fisher Syndrome
62
Multifocal Motor Neuropathy associated Antibody
Anti GM1 antibody
63
Headache Increased by standing and relieved by lying down.
Spontaneous Intracranial Hypotension
64
Feature to distinguish between true seizures and pseudo seizures
Lateral Tongue bite
65
Statin causing Peripheral Neuropathy
Simvastatin
66
Meningitis after cold and cough symptoms + working with children
Enterovirus Meningitis
67
Antiepileptic with renal stones as side effect
Topiramate
68
Cape Like distribution anesthesia seen in
Syringomyelia
69
Neck pain + Headache exacerbated by cough + Cape like anesthesia
Chiari Type 1 Malformation
70
Global Wasting of Intrinsic muscles of hand site of lesion
T1 nerve root
71
MRI finding of Subacute Combined Degeneration
Increased T2 Weighted signals in posterior column
72
MRI finding of Multiple Sclerosis
Diffuse Patchy white matter lesion on T2 Weighted images
73
Kyphoscoliosis + Bilateral Pes Cavus + LMN wekaness
Charcot-Marie-Tooth Disease
74
Downbeat Nystagmus associated with
Arnold-Chiari Malformation
75
Post Delivery + Dehydration + Seizures
Saggital Sinus Thrombosis
76
Which Immunoglobulin is most important for GBS
IgA
77
Differentiate Myasthenia from Lambert Eaton Clinically
Areflexia and Autonomic Symptoms
78
Ptosis + dysphagia + atrophy of temporalis
Myotonic Dystrophy Type 1
79
Cluster Headache prophylaxis
Verapamil
80
Creutzfeldt-Jakob disease MRI Finding
Increased Signal in pulvinar of thalamus
81
MRI Shows String of Bead appearance
Fibromuscular Dysplasia
82
Management of Multiple Sclerosis acute attack
Prednisolone 0.5 gm 1-0-0 x 5 days
83
Confirmatory test for Creutzfeldt-Jakob disease
RT- QulC on Lumbar Puncture
84
Weakness of Triceps, Brachioradialis and Extensor Digitorum
Radial Nerve
85
Young tremor + Heart Disease
Wilsons Disease
86
INO Side identification
Same as side of eye which can't adduct
87
Saturday Night Palsy location
Radial Nerve at Spiral Groove
88
Headache + Word finding difficulty seen in
Migraine with Aura
89
Drugs that commonly cause deterioration in myasthenia gravis
• D-penicillamine • Neuromuscular blocking agents, eg succinylcholine • Aminoglycoside and fluoroquinolone antibiotics • Antiarrhythmics, eg quinidine, procainamide • B-blockers, eg propranolol
90
Ropinirole Mechanism of Action
Dopamine receptor agonist
91
CSF shows increased opening pressure and decreased glucose
TB meningitis
92
Intrathecal synthesis of IgG seen in
Multiple Sclerosis
93
High ESR and pain in jaw along with headache
Giant Cell Arteritis
94
Satiety Center in brain is located at
Ventero Medial Nucleus
95
Sedative safest in Parkinsonism patients
Lorazepam
96
Management of Alzheimers Disease
- Donepezil - Rivastigmine
97
Reduce Dyskinesia in parkinson patient on L-Dopa
Amantadine
98
Increased T2 signal in frontal lobe white matter in MRI
Pick's Disease
99
DOC for Management of Muscle Weakness in Lambert Eaton
Amifampridine
100
Which CNS Cells are mainly destroyed in Osmotic demyelination
Astrocytes (Undergo apoptosis)
101
Genetic risk factor for Alzheimer’s Disease
APO E4 allele
102
Genetic risk factor for Alzheimer’s Disease
APO E4 allele
103
Anti Epileptic with least risk of heart block
Primidone
104
HIV + Neuro symptoms + single brain lesions with homogenous enhancement
Primary CNS lymphoma
105
High altitude cerebral edema management
Descent + Dexamethasone
106
Medications to Avoid in Dementia Patients
Anti Psychotics (Olanzapine)
107
Parkinson’s medicine for gambling person
Procyclidine
108
HIV patient with MRI brain shows Dilated Periventricular Spaces
Cryptococcal Infection