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MRCP Part 1 > Hematology > Flashcards

Hematology Flashcards

1
Q

Blood cancer associated with DIC

A

Acute Promyelocytic Leukemia

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2
Q

Microangiopathic Hemolytic Anemia + Thrombocytopenia

A

Thrombotic Thrombocytopenia Purpura

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3
Q

Livido Reticularis + Recurrent miscarriages

A

APLA Syndrome

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4
Q
A
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5
Q

Normocytic Anemia with Sideroblastic change

A

Lead poisoning

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6
Q

Jaundice + cholecystitis + anemia

A

Hereditary Spherocytosis

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7
Q

Hodgkin Lymphoma with best prognosis

A

Lymphocyte predominant

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8
Q

Hodgkin Lymphoma with worst prognosis

A

Lymphocyte depleted

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9
Q

Malaria + Anemia + Increased reticulocyte count + Acute Kidney injury

A

Blackwater Fever

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10
Q

Best way to detect protein c deficiency

A

Copperhead Snake Venom Assay

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11
Q

Protein C inhibits which clotting factors

A

Factors Va and VIIIa

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12
Q

Early Pregnancy blood transfusion extra screening test

A

Cytomegalovirus

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13
Q

Pneumococcal vaccine before splenectomy time

A

Minimum 14 days before

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14
Q

Most common complication of heparin induced thrombocytopenia

A

Deep Vein Thrombosis

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15
Q

Excessive bleedingg following dental extraction

A

Von-Willebrand’s Disease

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16
Q

Cold Agglutinins + Lymphadenopathy + Night Sweats

A

Non- Hodgkin’s Lymphoma

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17
Q

Chemotherapy agents causing Neuropathy

A
  1. Vincristine
  2. Cisplatin
  3. Paclitaxel
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18
Q

What is Mycosis fungoides

A

Cutaneous T-Cell Lymphoma

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18
Q

Anemia + Hypercalcemia + Lower back pain

A

Multiple Myeloma

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19
Q

CLL with anemia investigation to identify cause

A

Antiglobulin Test (Coombs test)

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20
Q

Prophylactic to reduce bleed during procedures in von willebrand disease

A

DDAVP + Tranexamic Acid

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21
Q

Causative Agent of Aplastic Crisis in Sickle Cell Disease

A

Parvovirus B19

22
Q

Autoantibodies responsible for Heparin-Induced Thrombocytopenia

A

Anti-heparin-PF4 antibodies.

23
Q

Late complication of Hodgkin Lymphoma after chemo

A

Secondary Acute Myeloid Leukemia

24
Q

Trephine biopsy showing fatty bone marrow

A

Aplastic Anemia

25
Q

Aplastic Anemia management

A

Hematopoetic Stem Cell Transplantation

26
Q

Most common type of Hodgkin’s Lymphoma

A

High Grade B cell Hodgkin’s Lymphoma

27
Q

Neck Lump Investigation of choice

A

Excision Biopsy

28
Q

Acute Myeloid Leukemia gene associated with worst prognosis

A

Chromosome 7 Abnormality

29
Q

Medicine to reduce risk of acute urate nephropathy in AML

A

Allopurinol and Rasburicase

30
Q

Nail finding Characteristic of Iron deficiency anemia

A

Koilonichya

31
Q

First Line Treatment for Chronic Myeloid Leukemia

A

Imatinib

32
Q

Drug of choice for DVT

A

Apixaban or Rivaroxaban

33
Q

Urine Dipstick positive for blood + no red cell seen on urine microscopy

A

Paroxysmal Nocturnal Hemoglobinuria

34
Q

Alteplase reversal Guidelines

A

FFP + Tranexamic Acid

35
Q

Sickle Cell disease with Low Urine Osmolality

A

Nephrogenic Diabetes Insipidus

36
Q

Leukemia + pancytopenia + LFT deranged + Diarrhea + Rash

A

Graft vs Host Disease

37
Q

Nephrotic Syndrome clotting cause

A
  1. Protein S
  2. Anti Thrombin
38
Q

Arthritis + Splenomegaly + Neutropenia

A

Felty’s Syndrome

39
Q

Investigation to assess prognosis of Multiple Myeloma

A

Serum Beta-2 Microglobulin

40
Q

Effective Management of Paroxysmal Nocturnal Hemoglobinuria

A

Eculizumab

41
Q

Burkitt Lymphoma gene

A

c-Myc

42
Q

Clinical Features of Primary Antiphospholipid syndrome

A
  1. DVT
  2. Livido Reticularis
  3. Thrombocytopenia
43
Q

Anemia + Increased Osmotic Fragility

A

Hereditary Spherocytosis

44
Q

Anemia + Cholecystitis

A

Hereditary Spherocytosis

45
Q

Essential Thrombocytosis management

A

Hydroxycarbamide and Aspirin

46
Q

Indication for Fresh Frozen Plasma Transfusion

A

Increased PT and APTT

47
Q

Indication for Platelet Transfusion

A

Active Bleeding + Decreased Platelet <50,000

48
Q

Heinz Body seen in

A

G6PD Deficiency

49
Q

Evan’s Syndrome

A

Autoimmune Hemolytic Anemia and ITP

50
Q

Inherited prothrombotic disorder in Northern Europe

A

Factor 5 leiden

51
Q

Hairy Cell Leukemia gene affected

A

BRAF gene

52
Q

Cells with abundant cytoplasm and broad based projections

A

Hairy Cell Leukemia

MRCP Part 1 (9 decks)

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