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MRCP Part 1 > Endocrinology > Flashcards

Endocrinology Flashcards

1
Q

DM + Obesity Dual OHA Drugs

A

Metformin + DPP4 Inhibitor

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2
Q

Cushinoid Features + Normal Dexamethasone suppression test

A

Psuedo Cushing Syndrome (Seen in Alcoholics)

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3
Q

Low sodium + Quadriparasis + Inability to swallow or speak

A

Central Pontine Myelinolysis

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4
Q

Thyroid Lymphoma Management

A

Chemotherapy + External Beam Radiotherapy

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5
Q

Amenorrhoea + Low LH and FSH

A

Hypothalamic Hypogonadism

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6
Q

Hypoglycemia with no cause identified

A

Inpatient 72 hour fasting and check insulin + C-peptide levels

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7
Q

Causes of Hypoglycemia

A

EXPLAIN
- EXogenous Drugs - Insulin,
- Pituitary Insufficiency
- Liver Failure
- Adrenal Failure
- Insulinomas
-Non-Pancreatic Neoplasms

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8
Q

Acromegaly Medical Management

A
  1. Cabergoline
  2. Octreotide
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9
Q

Differentia between MEN 1 and MEN 2

A

MEN 1 has angiofibromas not seen in MEN 2

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10
Q

SIADH Diagnosis

A
  • Serum Osmolality <275 mOsm
  • Urine Osmolality > 100 mOsm
  • Urine Sodium >30
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11
Q

Post Surgery follow up for thyroid cancer

A

TSH supression with thyroxine and dynamic risk stratification

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12
Q

Cushings Initial Investigations

A
  • 2 x 24 hour urine free cortisol
  • Overnight Dexamethasone suppression test
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13
Q

To differentiate pituitary adenoma and ectopic ACTH

A

High Dose Dexamethasone suppression test

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14
Q

Acromegaly Initial Test

A

IGF-1 Levels

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15
Q

MI + DM OHA of choice

A

SGLT2 - Empaglifozin

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16
Q

Diabetics undergoing strenuous exercise + Needs Insulin

A

Insulin Pump

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17
Q

Proximal Muscle weakness + Long Standing Diabetes

A

Diabetic Amyotrophy

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18
Q

Addisons + Amenorrhoea hormone responsible

A

Prolactin

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19
Q

Carbimazole + Sore Throat

A

Agranulocytosis

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20
Q

Elevated Parathyroid Hormone-related Protein (PTHrP) Seen in

A

Hypercalcemia of Malignancy

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21
Q

On Multiple Anti hypertensives but Hypertension + Hyperkalemia

A

Conn’s Syndrome

22
Q

Amiodarone Induced Thyrotoxicosis Management

A

Antithyroid Drugs + Corticosteroids

23
Q
  • Short Stature
  • Shortening of fourth and fifth metacarpals
  • Basal Ganglia Calcification
    Seen in
A

Pseudohypoparathyroidism

24
Q

Anti-Thyroid Peroxidase antibodies + Post partum

A

Post partum Thyroiditis

25
Q

Anti TSH Receptor Antibody

A

Graves Disease

26
Q

Pheochromocytoma management

A

Alpha Blocker then Beta Blocker Then Surgery

27
Q

Cranial Nerve Palsy + Headache + Hypotension

A

Pituitary Apoplexy

28
Q

Cushings Disease on ABG

A

Hypochloremic Metabolic Alkalosis

29
Q

On Metformin + Risk of CVD next OHA is?

A

SGLT2 Inhibitors

30
Q

Hyperthyroidism + Viral Prodrome preceding

A

De-Quervains Thyroiditis

31
Q

Pheochromocytoma but no CT finding - Next Investigation

A

Metaiodobenzylguanidine (MIBG) Scan

32
Q

High T4 + Low TSH + Scintigraphy shows low uptake by gland

A

Thyrotoxicosis Factitia

33
Q

First Sign of Onset of Puberty in Females

A

Breast Bud Development

34
Q

Female External Genitalia + Absence of hair growth + No Menses

A

Androgen Insensitivity Syndrome

35
Q

Medullary Thyroid Cancer + High Blood Pressure

A

Phaeochromocytoma due to MEN-2a

36
Q

OTC Antacids + Increased Ca2+ and Bicarbonate levels in blood

A

Milk-Alkali Syndrome

37
Q

Adrenal Crisis Management

A

IV NS + IV Hydrocortisone

38
Q

Increased Prolactin + Myxoma + Spotty Pigmentation

A

Carney’s Syndrome

39
Q

Young + Normal Anion Gap Metabolic Acidosis + Abdominal Pain

A

Addisons Disease

40
Q

Cerebellar Hemorrhage + Retinal Angioma + Retinal Detachment

A

Von Hippel Lindau Disease

41
Q

Low BMI + Young women + Strenuous Exercise + Amenorrhoea

A

Premature Ovarian FailureH

42
Q

Hormone Responsible for Epiphyseal Fusion and Cessation of Growth

A

Oestrogen

43
Q

Hormone to test Presence of Ovulation

A

Luteinizing Hormone

44
Q

Diagnosed as Type 2 DM but Urine ketones + despite OHA

A

Latent Autoimmune Diabetes of Adulthood

45
Q

Lack of sense of smell + Normal Height + Small Testis

A

Kallmann Syndrome

46
Q

Graves Eye Disease worsened by:

A

Radioiodine

47
Q

Management of Secondary Hyperparathyroidism

A

Calcium and 1 alpha calcidiol

48
Q

Glucagonoma Dermatological Finding

A

Necrolytic Migratory Erythema

49
Q

ABG Finding in Hyperthyroid Patients

A

Decreased PaCO2

50
Q

Pagets Disease on Bone Biopsy

A

Multinucleated Osteoclasts

51
Q

Investigation to know volume thyroid

A

Ultrasound Scan

52
Q

High TSH
High Free T4 and T3

A

Poor compliance with medication

MRCP Part 1 (9 decks)

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