Rhabdomyolysis Flashcards

1
Q

What is the pathophysiology of rhabdomyolysis?

A

rapid breakdown of skeletal muscle leads to acute tubular necrosis

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2
Q

What can cause rhabdomyolysis?

A
Crush injury
Strenuous exercise ge seizure 
Medications- statins, SSRIs, diuretics 
Drug abuse
Others
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3
Q

What is the presentation of rhabdomyolysis?

A
Dark brown tea coloured urine= classic 
AKI with disproportionately raised CK
Muscle pain
Weakness
Vomiting
Confusion
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4
Q

What investigations are done for rhabdomyolysis?

A
URinalysis- haematuria, red cell casts
Bloods:
-CK >1000
-hypocalcaemia
-hyperphosphataemia, hyperkalaemia
-metabolic acidosis
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5
Q

What is the management of rhabdomyolysis?

A

Large volume IV fluids
Corret electrolyte abnormalities
-Hyperkalaemia= IV calcium gluconate, insulin-dextrose
Severe= dialysis

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6
Q

What are some complications of rhabdomyolysis?

A

AKI
Electrolyte abnormalities
DIC

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