Bone tumours Flashcards
What is the most common bone tumour?
Metastatic by ~25x
Where are the common sites for metastatic bone disease in order?
Vertebrae Proximal femur and pelvis Ribs Sternum Skull
What are the most common cancers for bone mets, in order?
PRostate
Breast
Lung
What are the common cancers that met to the bones?
Prostate, breast, lung= most common Kidney Thyroid GI Melanoma
What is the presentation of bone mets?
Increasing bone pain- dull ace, worse at night Pathological fracture Spinal cord compression Hypercalcaemia Anaemia Decreased mobility
What investigations are done for bone mets?
XR
CT/MRI, isotope bone scan
Fracture risk
What is sued for fracture risk in bone mets?
Mirel’s score
What Mirel’s score indicated high fracture risk?
> 8
What would a high Mirel’s score indicate?
Prophylactic fixation
What is the management of bone mets?
Radiotherapy
Surgery- prophylactic fixation, eradication
Analgesia
Wat is the prognosis with bone mets?
Poor prognostic indicator
Who is osteosarcoma usually seen in?
10-20yo
What are the most common sites for osteosarcoma?
Femur= most common
Tibia, humerus
What is the presentation of osteosarcoma?
Persistent bone pain, worse at night
Bone swelling, palpable mass
Restricted joint movement
What does unexplained bone pain/swelling indicate?
Urgent XR within 48 hours