Rh & ABO Flashcards

1
Q
A
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2
Q

def of Rh Isoimmunization

A
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3
Q

Etiology of Rh Isoimmunization

A
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4
Q

Etiology of Rh Isoimmunization

  • Any contact () Rh + ve fetal blood & maternal circulation
A
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5
Q

Etiology of Rh Isoimmunization

  • Blood transfusion of Rh +ve blood to Rh -ve female at any age
A

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6
Q

CP of Rh Isoimmunization

A
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7
Q

CP of Rh Isoimmunization

  • Degrees
A
  • Congenital hemolytic anemia: Mildest form
  • Icterus gravis neonatorum: Commonest form
  • Fetal hydrops: Rarest & most severe form
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8
Q

CP of Rh Isoimmunization

  • Icterus gravis neonatorum
A
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9
Q

Dx of Rh Isoimmunziation

  • US
A
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10
Q

Spectrophotometric analysis of AF in Rh Isoimmunization

  • Indications
A
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11
Q

Fetal Blood Sampling in Rh Isoimmunization

A
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12
Q

Fetal Blood Sampling in Rh Isoimmunization

  • Aim
A
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13
Q

Fetal Blood Sampling in Rh Isoimmunization

  • Disadvantages
A

Complications of cordocentesis:

  1. More risky than serial amniocentesis.
  2. Feto-maternal Hge & consequently, massive ↑↑ in concentration of Abs.
  3. Thrombosis of umbilical vessels.
  4. Risk of fetal death (1.5%).
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14
Q

Neonatal Blood Sampling in Rh Isoimmunization

A
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15
Q

Prevention of Rh Isoimmunization

A
  • Prevention of blood transfusion errors
  • Anti-D Ig administration
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16
Q

Prevention of Rh Isoimmunization

  • Prevention of blood transfusion errors
A

Never to give Rh +ve blood to Rh -ve females.

17
Q

Prevention of Rh Isoimmunization

  • Anti-D Ig administration
A
18
Q

Anti-D Ig administration in Rh Isoimmunization

  • Value
A

Anti-D Ig will destroy Rh +ve RBCs in maternal Circulation before sensitization.

19
Q

Anti-D Ig administration in Rh Isoimmunization

  • indications
A
20
Q

Anti-D Ig administration in Rh Isoimmunization

  • time of adminstartion
A

Within 72 hours after sensitizing event.

21
Q

Anti-D Ig administration in Rh Isoimmunization

  • Calculation of Dose
A
22
Q

Plan managment in Rh Isoimmunization

  • Algorithm
A
23
Q

Intrauterine transfusion (IUT) in Rh Isoimmunization

  • indications
A
  • Fetal hydrops
  • significant fetal anemia (Hb deficit > 2 gm/dl from mean for normal fetuses or Hct value < 30%).
24
Q

Neonatal Care in Rh Isoimmunization

  • exchange Transfusion
A
25
Q

Criteria to Dx ABO Isoimmunization

A
26
Q

Def of Non-Immune Fetal Hydrops

A
27
Q

Etiology of Non-Immune Fetal Hydrops

A
28
Q

Dx of Non-Immune Fetal Hydrops

A