DM Flashcards
Modified White Classification of DM in Pregnancy
Modified White Classification of DM in Pregnancy
- A1 & A2
- A1: → FBS < 105 mg/d| & PPS < 120 mg/di.
A2: → FBS > 105 mg/dl & PPS > 120 mg/dl.
RF for GDM
Effects of Pregnancy on DM
- Pregnancy is Diabetogenic
- Change in Insulin Requirments
- Increased Incidence of DM Complications
- Aggravation of Retinopathy & Nephropathy
Effects of DM on Pregnancy
Maternal & Fetal & Neonatal
Maternal Effects of DM on Pregnancy
- During Pregnancy
- During labor
- During Puerperium
- Late Complications
Maternal Effects of DM on Pregnancy
- Abortion
Due to Ag-Ab reaction associating DM or chromosomal abnormalities.
Maternal Effects of DM on Pregnancy
- Preterm Labor
3-4 times higher in diabetics (MgSO4 is the tocolytic of choice).
Maternal Effects of DM on Pregnancy
- Polyhydraminos
Maternal Effects of DM on Pregnancy
- HTN
Due to vasculopathy or nephropathy.
Maternal Effects of DM on Pregnancy
- Infection
UTI, vulvovaginitis (monilia) or chorioamnionitis (after ROM).
Maternal Effects of DM on Pregnancy
- During Pregnancy
Maternal Effects of DM on Pregnancy
- During Labor
Maternal Effects of DM on Pregnancy
- During puerperium
- PPH & puerperal sepsis.
- Abnormal lactation: Due to changes in glucose level.
Maternal Effects of DM on Pregnancy
- Late Complications
50% of cases è GDM will develop overt DM later on.
Neonatal Effects of DM on Pregnancy
- Respiratory distress syndrome (RDS)
- Hypertrophic cardiomyopathy
- Hypoglycemia
- Hypocalcemia & hypomagnesemia
- Hyperbilirubinemia
- Polycythemia
- Poor Feeding
- Birth Trauma
- Late Complications
Neonatal Effects of DM on Pregnancy
- RDS
- Due to delayed lung maturity (because hyperinsulinemia inhibits secretion of pulmonary surfactant).
Neonatal Effects of DM on Pregnancy
- Hypoglycemia
Blood glucose level < 40 mg/d| (due to hyperinsulinemia)
Neonatal Effects of DM on Pregnancy
- Hyperbilirubenemia
Due to delay in liver maturation.
Neonatal Effects of DM on Pregnancy
- Polycythemia
Hct value > 65% (due to chronic intrauterine hypoxia → T T erythropoietin production).
Neonatal Effects of DM on Pregnancy
- Poor Feeding
Due to prematurity, RDS or congenital anomalies
Neonatal Effects of DM on Pregnancy
- Late Complications
Increased risk of development of type I DM later in life (1-3% if mother only is diseased & 6% if father is diseased also
Fetal Effects of DM on Pregnancy
- Congenital Anomalies
- Macrosomia
- IUGR
- IUFD