Prematurity Flashcards
Etiology & RF for Prematurity
Etiology & RF for Prematurity
- Maternal Factors
Etiology & RF for Prematurity
- fetal Factors
1) Fetal anomalies
2) multiple infections as TORCH
3) IUFD.
Etiology & RF for Prematurity
- obstetric Compications
1) Polyhydramnios, PPROM
2) Chorioamnionitis
3) placenta previa, placental abruption
4) pregnancy on top of IUD.
Etiology & RF for Prematurity
- Iatrogenic Factors
1) Premature induction of labor
2) ECV
3) amniocentesis or surgery.
Etiology & RF for Prematurity
- Idiopathic
In 50% of cases
Etiology & RF for Prematurity
- Commonest Cause
Idiopathic
Complications of Prematurity
- Long term
- Short term
Complications of Prematurity
- Long-term
- ↑↑ incidence of underdevelopment.
- ↑↑ incidence neurological & intellectual abnormalities later in life.
Complications of Prematurity
- short Term
- Respiratory
- Brain
- Blood
- Metabolic
- Others
Short term Complications of Prematurity
- Respiratory
Dx of Preterm Labor
- Prediction
- Manifestations of threatened preterm labor
- Criteria to document preterm labor
Dx of Preterm Labor
- Prediction
Dx of Preterm Labor
- Manifestations
Dx of Preterm Labor
- Criteria
Dx of Prematurity
- Before delivery
- After delivery (Features of prematurity at birth)
Dx of Prematurity
- Before Delivery
Tests for determination of fetal maturity
Dx of Prematurity
- After Delivery
Prevention of Preterm Labor
- General
- Rest
- Cervical Cerclage
- Prophylactic tocolytic
Prevention of Preterm Labor
- general Measures
Prevention of Preterm Labor
- rest
In high risk cases as in:
- cervical incompetence, multifetal pregnancy.
- previous preterm labor, PPROM or after uterine manipulation
Prevention of Preterm Labor
- cervical Cerclage
Done when indicated as in:
- cervical incompetence, uterine anomalies
- multifetal pregnancy or previous preterm labor
Prevention of Preterm Labor
- tocolytics
Not recommended
Managment of Preterm Labor
- Bed Rest
- Sedatives & narcotics
- Tocolytics
- Corticosteroides
- managment of Delivery
- Neonatal Care
Managment of Preterm Labor
- Sedatives & Narcotics
As barbiturates, diazepam & pethidine:
▪ these agents depress preterm infant when administrated to mother near time of delivery
Managment of Preterm Labor
- Bed Rest
Preferably in Lt lateral position to improve uterine blood flow.
Managment of Preterm Labor
- Tocolytics
Types of Tocolytics
- Short term
- Long term
Def of Tocolytics
Tocolytics are drugs that inhibit uterine contractions.
Types of Tocolytics
- Short term
Indicated to:
- Delay labor 2-3 days till achieving max. effect of steroids.
- Prevent preterm labor after abdominal or cervical
operations or uterine manipulation.
Tocolytics
- If pregnancy is ( ) 34 & 37 weeks
- Decision of tocolysis depends on quality of care available for premature infants & estimated fetal weight
Types of Tocolytics
- Long term
Not effective(oral):
- As they stop uterine contractions temporarily but rarely prevent preterm birth
CI of Tocolytics
Tocolytics
- Drugs Used
- β-agonists
- Magnesium sulfate (MgSO4)
- PG synthetase inhibitors (anti-PGs)
- Ca++ channel blockers (Nifedepine).
- Oxytocin antagonists (atosiban)
- Progesterone(17 α-Hydroxyprogesterone caproate)
- Others
Management of delivery (conduct of preterm labor)
- Place
- In well equipped hospital with availability of neonatal intensive care & neonatologist efficient in resuscitative techniques present at delivery room
Management of delivery (conduct of preterm labor)
- Methods
Management of delivery (conduct of preterm labor)
- Vaginal
Vaginal Delivery of Preterm Labor
- During 1st stage
Vaginal Delivery of Preterm Labor
- During 2nd Stage
Important precautions:
- Generous episiotomy once head reaches perineum.
- Outlet forceps is the only type of forceps allowable.
- Ventouse is contraindicated.
- No vigorous manipulations
Vaginal Delivery of Preterm Labor
- during 3rd stage
As normal labor.
CS Delivery of Preterm Labor