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mrcog part 1 > Revision notes: 8. Immunology > Flashcards

Revision notes: 8. Immunology Flashcards

1
Q

Which type of hypersensitivity

Pernicious anaemia
Graves
Myasthenia gravis

A

Type 2 - antibody dependent

Complement activation via classical pathway

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2
Q

Which type of hypersensitivity

Rheumatoid
SLE
Glomerulonephritis

A

Type 3 - Immune complex deposition

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3
Q

Which type of hypersensitivity

Graft rejection

A

Type 4 - cell-mediated

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4
Q

Examples of attenuated vaccines

A

MMRBOYV

Mumps
Measles
Rubella
BCG
Polio
Yellow fever
Varicella
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5
Q

When does maternal IgG begin crossing placenta

A

12 weeks

peak at 32 weeks

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6
Q

What happens to TH-1 dependent conditions e.g. rheumatoid during pregnancy

A

Gets better

Progesterone suppresses TH-1

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7
Q

What happens to TH-2 dependent conditions during pregnancy

A

Get worse

E.g. SLE

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8
Q

When does foetus start making IgM

A

11 weeks

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9
Q

Measles mumps and rubella are all …. containing viruses

A

RNA

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10
Q

Intracellular bacteria

A

Chlamydia
Legionella
Mycobacterium TB
Coxiella

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11
Q

Plasma concentration of IgA

A

200mg/dL

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12
Q

Cancer marker for medullary thyroid cancer

A

carcinoembryonic antigen

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13
Q

Gardasil works against which HPV strains

A

6, 11, 16, 18

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14
Q

Inactivated bacterial vaccines

A

Tetanus

Diptheria

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15
Q

Inactivated viral vaccines

A

Polio
Influenza
Rabies
Hepatitis A

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16
Q

CD4+ T helper cells are divided into Th1 and Th2

Which secretes pro-inflammatory cytokines?

A

Th1

17
Q

Which immunoglobulin is a dimer

A

IgA

18
Q

HPV vaccine offers protection against which cancers

A 
Cervical
Vaginal
Vulval
Anal
Oropharyngeal
19
Q

Antigen presenting cells of the cervix

A

Langerhans

20
Q

Monocytes make up ….. % of total leukocyte count

A

2-10%

21
Q

Which vaccine type is absolutely contraindicated during pregnancy

A

Live-attenuated

22
Q

CD3 - expressed by what

A

Co-receptor expressed by CD4+ and CD8+ T cells

23
Q

Side effects of metronidazole

A

Urine discolouration
Peripheral neuropathy

24
Q
A

mrcog part 1 (14 decks)

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