Revision notes: 2. Embryology Flashcards

1
Q

Name for 16 cell zygote

A

Morula

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2
Q

Syncitiotrophoblast secretes?

A

hCG

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3
Q

Process involving formation of 3 germ layers

A

gastrulation
occurs in 3rd week of development

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4
Q

Ectoderm forms

A

epidermis
nervous system

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5
Q

mesoderm forms

A

muscles
skeletal system
connective tissues

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6
Q

endoderm forms

A

GIT
respiratory tract
endocrine glands
auditory system
urinary system

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7
Q

At what stage does the embryo obtain nutrient from maternal blood via uteroplacental circulation

A

Day 12

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8
Q

primary chorionic villi formed from

A

cytotrophoblasts

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9
Q

neural plate formed at day

A

day 18

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10
Q

primitive heart tube formed at

A

day 20

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11
Q

1st pharyngeal arch

A

Trigeminal nerve

Muscles of mastication

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12
Q

2nd pharyngeal arch

A

Facial nerve (VII)

Muscles of facial expression

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13
Q

3rd pharyngeal arch

A

Glossopharyngeal nerve

Muscle: stylopharyngeus

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14
Q

4th and 6th pharyngeal arch

A

Vagus nerve

4th arch: cricothyroid, pharyngeal

6th arch: muscles of larynx and oesophagus

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15
Q

Diagram of pharyngeal arches

A
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16
Q

Which structure is primary mechanism for shunting blood away from foetal pulmonary circulation

A

Foramen Ovale

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17
Q

Which structures develop from mesodermal somites

A

Dermis - dermatomes

Skeletal mucsle - myotomes

Tendons and cartilage - syndetomes

Bone - sclerotomes

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18
Q

Another name for paramesonephric ducts

A

Mullerian ducts

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19
Q

A bicornuate uterus is due to what?

A

Abnormal fusion and reabsorption of mullerian ducts

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20
Q

Which structure forms the kidney

A

metanephros

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21
Q

Mechanism of closure of ductus arteriosus

A

1st breath leading to inc arterial PO2

Increased bradykinin from lungs, stimulating smooth muscle constriction of ductus

DROP in prostaglandin E2

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22
Q

What percentage of people have a Meckel’s diverticulum

A

2%

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23
Q

Most potent prostaglandin for maintaining patency of DA during pregnancy

A

Prostaglandin E2

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24
Q

Somites are derived from which germ layer

A

Para-axial mesoderm

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25
Q

Diagram of spermatogenesis

A
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26
Q

In non-pregnant state, which hormones does the corpus luteum secrete

A

Progesterone (17a hydroxyprogesterone)

Oestradiol

Inhibin A

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27
Q

Which germ layer does the myenteric plexus of the GI tract develop

A

Neural crest of ectoderm

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28
Q

At term the placenta receives what percentage of uterine blood flow

A

90%

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29
Q

All hindgut structures are innervated by

A

T12/L1

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30
Q

Mullerian agensis otherwise known as

A

Rokitansky-Kuster-Hauser syndrome

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31
Q

Rathke pouch forms what

A

Adenohypophysis of pituitary gland

i.e. anterior pituitary

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32
Q

Kidney develops from which germ layer

A

Intermediate mesoderm

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33
Q

When does meconium first appear in fetal terminal ileum

A

10-16 weeks gestation

34
Q

Primary site of prostaglandin E2 production

A

All cells tbh, but placenta and ductus arteriosus have particularly high quanitities of COX enzyme isoforms required for PGE2 synthesis

35
Q

How many days post fertilisation does the blastocyst enter uterine cavity

A

4

36
Q

Kidney forms from the

A

Metanephric mesoderm

37
Q

Metanephros is functional from week?

A

10

38
Q

Which vessel obstructs ascent of kidney leading to horseshoe kidney

A

Inferior mesenteric artery

39
Q

Embryological origin of Allantois

A

Endoderm

40
Q

Embrylogical origin of distal 1/3rd of anal canal

A

Ectoderm of Cloaca

The Pectinate or Dentate line marks junction

41
Q

Which part of the placenta is in contact with maternal blood

A

Syncitiotrophoblast

42
Q

The collecting tubules of the kidney develop from

A

Metanephric mesoderm

43
Q

The liver and biliary tree develop from the

A

Distal Foregut Endoderm

The liver develops as an outgrowth of the endoderm of the distal foregut, as does the gall bladder, bile and cystic ducts.

44
Q

Gartner’s cyst - embryological origin

A

Mesonephric duct

45
Q

The round ligament is a remnant of the

A

Gubernaculum

46
Q

The inner cell mass differentiates into

A

Epiblast and hypoblast

Becomes bilaminar disc

47
Q

Primary chorionic villi form from the

A

cytotrophoblasts

48
Q

Primitive heart tube forms at day

A

20

49
Q

Intra-embryonic mesoderm forms from the

A

Ectoderm

50
Q

Para-axial mesoderm forms

A

somites

51
Q

Intermediate mesoderm forms

A

Urogenital system

52
Q

Lateral plate mesoderm forms

A

Somatic and splanchnic mesoderm

53
Q

Intra-embryonic coelom forms

A

Pericardial cavity

Pleural cavity

Peritoneal cavity

54
Q

Maternal parts of the placenta are derived from

A

Decidua Basalis

55
Q

Which villi contain blood vessels

A

Tertiary chorionic villi

56
Q

Placenta increta meaning

A

Invades myometrium but has not breached uterine serosa

57
Q

placentra percreta meaning

A

Has breached uterus serosa

58
Q

which intervertebral disc component is formed form the notocord?

A

nucleus pulposus

59
Q

Bartholin’s glands - embryonic origin

A

Urogenital sinus

60
Q

Paramesonephric duct in females (otherwise known as mullerian duct)

A

Forms: Uterovaginal canal (uterus, cervix, fallopian tubes, upper half of vagina), broad ligament

61
Q

Penile urethra forms from

A

Cloacal fold

62
Q

The obliterated umbilical vein becomes the

A

ligamentum teres

63
Q

Whenever the intestinal midgut loop fails to return from the umbilical cord into the abdominal cavity, the defect is known as

A

Exomphalos

64
Q

Gastroschisis is distinguishable from exomphalos in that exomphalos

A

Is covered by peritoneum and amnion

65
Q

Which part of the female urogenital system is described as the Vestibule?

A

Area between labia minora

66
Q

Which molecule plays an important role in capacitation?

A

Heparin

67
Q

What are the components of Placental barrier at term?

A

Syncitiotrophoblast and Endothelium

68
Q

How many oocytes are available at the time of puberty?

A

400,000

69
Q

The intraembryonic coelom forms within which structure?

A

Lateral plate mesoderm

70
Q

At what age does meconium appear in Fetal terminal ilium

A

10-16 weeks

71
Q

Which structure is the origin of the vas deferens

A

Mesonephric duct

72
Q

Thyroid cartilage and cricothyroid muscle develop from which Pharyngeal Arch

A

4th arch

73
Q

External Carotid artery develops from the

A

1st pharyngeal arch

74
Q

Common and internal carotid artery develop from the

A

3rd pharyngeal arch

75
Q

Morula forms on day what after fertilisation

A

Day 4

76
Q

The 7th cranial nerve develops from which pharyngeal arch

A

2nd arch

77
Q

Intrinsic muscles of larynx form from which pharyngeal arch

A

6th arch

78
Q

Subclavian artery develops from which pharyngeal arch

A

4th arch

79
Q

Muscles of facial expression - which pharyngeal arch?

A

Muscles of facial expression

80
Q
A