Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Respiratory Week 3 > Restrictive Lung Disease > Flashcards

Restrictive Lung Disease Flashcards

1
Q

what is a common exposure for small airways disease?

A

smoke pits…tour in afghanistan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what does small airways disease…obstructive or restrictive airway disease?

A

obstructive…anything with the airways is always obstructive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

name three ways to effect the chest wall and restrict it

A

mordib obesity
kyphoscoliosis
fibrothorax

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

name four things that cause weakness of respiratory muscles

A

polia
myasthenia gravis
guillian baree
amyotrophic lateral sclerosis (ALS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

name two things that cause abnormalities of lung parenchyma

A

sarcoidosis

idiopathic pulmonary fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how does ILD affect TLC, FRC and RV?

A

they are all decreased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

how does muscle weakness affect TLC, FRC and RV?

A

TLC decreased FRC normal and RV increased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

how does obesity affect TLC, FRC, and RV?

A

TLC slightly reduced or normal
FRC REDUCED
RV normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is the tip off lung volume change for obesity?

A

reduced FRC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is another name for interstitial lung disease?

A

diffuse parnehcymal Lung disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

in restrictive disease…does compliance increase of decrease?

A

decreased!!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

how does ILD affect the FVC?

A

it lowers it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

how does ratio of FEV1/FVC change in ILD?

A

it will be normal or high

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how does ILD affect DLCO?

A

it takes longer for the oxygen to diffuse..so DLCO is decreased compared to normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are two common signs of cor pulmonale?

A

jugular venous distension

peripheral edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is the most common disease that mimics ILD?

A

congestive heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

is silicosis an upper or lower lobe disease?

A

upper lobe

18
Q

what does silicosis cause?

A

calcification in the upper love

19
Q

is asbestosis an upper or lower lobe lung disease?

A

lower lobe disease

20
Q

what is a histological finding in asbestosis?

A

ferruganous bodies, iron deposits

21
Q

is coal worker pneumoconiosis an upper or lower lobe disease?

A

upper lobe

22
Q

what is the gold standard imaging for ILD?

A

high resolution CT

23
Q

what does ground glass on a CT suggest in ILD?

A

active inflammation

24
Q

what CT finding does diffuse alveolar hemorrhage?

A

ground glass…due to bloody

25
Q

is IPF in lower or upper lobes?

A

lower lobes..

26
Q

what ILD does clubbing signal?

A

IPF

27
Q

explain the disease mechanism in IPF

A

injury to epithelium causes cytokine release that activates myofibroblasts instead of epithelial recovery..leads to collagen deposition

28
Q

what does it mean for granuloma to be non caseating?

A

no necrotizing in the middle of the granuloma

29
Q

what cells make up the granuloma in sarcoid?

A

macrophages, histiocytes, lymphocytes and dendritic cells

30
Q

what cytokines are associated with sarcoidosis? what T cell?

A

IFN-gamma
IL2
IL12

Th1

31
Q

is sarcoidosis caused by antigens or nah?

A

questionable…maybe non TB myco in US

32
Q

after development of granulomas in saroidosis…what can happen to them?

A

can either self resolve or progress to fibrotic tissue

33
Q

is sarcoidosis an upper or lower lobe disease?

A

upper lobe

34
Q

how to diagnose sarcoidosis?

A

bronchoscopy…must have proof of granulomas

35
Q

what two things must you see to diagnose Sarcoid?

A

granulomas

no evidence of cancer, infection with TB or fungus

36
Q

what are cutaneous granulomas called in sarcoid?

A

lupus pernio

37
Q

name a kidney finding with sarcoidosis?

A

hypercalcemia leading to nodules in the kidney

38
Q

what molecule leads to hypercalcemia in sarcoid?

A

alpha 1 hydroxylase

39
Q

name three common causes of diffuse alveolar hemorrhage

A

goodpasture syndrome
microscopic polyangitis
granulomatous with polyangitis

40
Q

what two molecules associated with kidneys are elevated in sarcoidosis?

A

ACE and Calcium

41
Q

what are the four stages of sarcoidosis?

A

1-lymphadenopathy hilar
2/3- lung parenchyma involvement
4- fibrosis

42
Q

what is the treatment for sarcoidosis? when should it be initiated?

A

corticosteroids when symptomatic

Respiratory Week 3 (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions