Respiratory tract infections Flashcards
What is the clinical presentation of influenza?
Fever Malaise- feeling uneasy Myalgia- muscle pain headache Cough Prostration
What are the types of ‘classical’ flu viruses?
Influenza A
Influenza B
What is a type of ‘Flu-like’ illnesses?
parainfluenza viruses
How can flu be transmitted?
Droplets/direct contac
when is influenzal pneumonia likely to be seen?
In pandemic years
What pneumonia are associated with flu?
Primary influenzal pneumonia
secondary bacterial pneumonia
who is at risk of primary influenzal pneumonia?
yound adults
who is at risk of secondary bacterial pneumonia?
infants, elderly, debilitated, pre-existing disease, pregnant women
What is the symptomatic treatment of flu?
bed rest
fluids
paracetamol
what are some antivirals for flu?
Osetamivir
Zanamivir
when do NICE say antivirals should be given?
to patients at risk of complications when flu is circulating/ early in disease
What is the main cause of epidemics?
antigen shift
What is the genome of influenza like?
multiple segments
what factors can bring about new flu strains?
Antigenic shift
segmented genome
animal reservoir
which flu is associated with birds?
Avian flu
How do you confirm flu in a lab?
mostly by PCR
antibody detection
What types of vaccines can be used to prevent flu?
Killed vaccine
Live attenuated vaccine (Given to children aged 2-17)
Antivirals
What bacteria are associated with community acquired pneumonia?
Mycoplasma pneumoniae
Coxiella burnetii
Chlamydophila psittaci
What caused Q fever?
coxiella burnetii
which bacteria is associated with sheep and goats?
coxiella burnetii
what is a complication of coxiella burnetii?
Culture negative endocarditis
what animals can spread pneumonia?
parrots, budgies, cockatiels
what are the clinical presentations of brochiolitis?
age 1 or 2 fever coryza cough wheeze
(sometimes grunting, decreased PaO2, intercostal/sternal indrawing)
what age groups have the highest incidence of mycoplasma pneumoniae?
Children
Young adults