Pleural Malignancy Flashcards

1
Q

What is a pleural effusion?

A

Abnormal collection of fluid in pleural space

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2
Q

what is a PA CXR?

A

posterior- anterior chest x-ray

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3
Q

What tests would you take for a pleural effusion?

A
PA CXR
Pleural aspirate
Biochemsitry
Cytology
Culture
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4
Q

what would straw-coloured pleural fluid indicate?

A

Cardiac failure

hypoalbuminaemia

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5
Q

what would bloody pleural fluid indicate?

A

Trauma
Malignancy
Infection
Infarction

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6
Q

What would milky pleural fluid indicate?

A

Empyema

chylothorax

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7
Q

What would foul smelling pleural sample indicate?

A

Anaerobic empyema

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8
Q

what would food particles in pleural fluid indicate?

A

oesophageal rupture

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9
Q

whats the first test you would send pleural fluid off to?

A

Biochemistry

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10
Q

A protein count of >30 d/L indicates?

A

Transudates

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11
Q

a protein count of <30 g/L indicate?

A

Exudates

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12
Q

what do cytology look for?

A

Malignant cells
lymphocytes
neutrophils

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13
Q

what is the major cause of pleural malignancy?

A

mesothilioma

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14
Q

How do you take a tissue biopsy?

A

Blind percultaneous pleural biopsy
CT image guided cutting needle pleural biopsy
thoracoscopy

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15
Q

what occupations are related to mesosthelioma?

A

Builders, shipyard workers etc. who have worked with asbestos

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16
Q

what are symptoms of mesothelioma?

A
breathlessness
chest pain
weight loss
fever
sweating
cough
17
Q

what is asbestosis?

A

hardening of the lungs as a result of asbestos exposure

18
Q

what are the three main types of asbestos?

A

Chrysotile
Amosite
Crocidolite

19
Q

Why would you image to investigate mesothelioma?

A

To look for pleural nodularity
circumferential pleural thickening
local invasion
lung entrapment

20
Q

what would you find in pleural fluid aspiration in mesothelioma?

A

Low cytological yield

Avoid repeated aspiration

21
Q

what are some mesothelioma treatments?

A
pleurodese effusions
radiotherapy
surgery
chemo
palliative care
22
Q

what can cause malignant pleural effusions?

A
Metastasis of 
lung cancer (adenocarcinoma?)
breast cancer
upper GI
lymphoma 
melanoma
ovarian etc.
23
Q

What is talc?

A

a sclerosing agent

mixed with saline and some other liquids & injected into pleural space

24
Q

what are side effects of talc pleurodesis?

A
Minor pleuritic pain &amp; fever
Pneumonia
Resp. failur
talc pneumonitis/ARDS
secondary empyema
local tumor impplantation at port sitein mesothelioma
25
Q

when might a pleural catheters be used?

A

in patients with malignant effusions

26
Q

What is the LENT score?

A

LDH
ECOG PS
Neutrophil to lyphocyte ration
Tumour type

27
Q

What is a primary pneumothorax?

A

normal lungs

apical bullae rupture

28
Q

what is a secondary pneumothorax?

A

underlying lung disease (eg COPD)