Respiratory Pharmocology

Question 1

What are antihistamines?

Answer 1

Inhibit smooth muscle contraction in blood vessels and respiratory/GI tracts. Decrease capillary permeability.

Question 2

What are the characteristics of 1st generation of histamines? Examples?

Answer 2

Cross the BBB and are sedative. Benadryl, Dramamine.

Question 3

What are the characteristics of 2nd generation histamines? Examples?

Answer 3

Cant cross BBB, non-sedative. Longer half-lives.

Allegra, Claritin, Clarinex, Zyrtec, Semprex-d.

Question 4

What do H1 Antagonists do?

Answer 4

Block pain and itch. Block vasodilation. Block Bronchoconstriction.

Question 5

What are nasal decongestants?

Answer 5

Relieve nasal obstruction and discharge.

Question 6

What are Antitussives?

Answer 6

Suppress cough by depressing center in medulla or increasing flow of saliva.

Question 7

What are expectorants?

Answer 7

Liquefy respiratory secretions.

Question 8

What are mucolytics?

Answer 8

By inhalation to liquefy mucous.