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USMLE > Respiratory Drugs Reverse > Flashcards

Respiratory Drugs Reverse Flashcards

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USMLE® Step 1 flashcards
1
Q

A agonists

A

Pseudoephedrine, Phenylephrine - mech

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2
Q

Acute exacerbation of asthma

A

Albuterol - use

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3
Q

Allergic asthma resistant to inhaled steroids and long-acting B2 agonists

A

Omalizumab - use

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4
Q

Allergy

A

Loratidine, Fexofendaine, Desloratadine - use

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5
Q

Allergy
Motion sickness
Sleep aid

A

Dipenhydramine, Dimenhydrinate, Chlorpheniramine - use

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6
Q

Antileukotreine that blocks leukotriene receptors (CysLT1)

A

Montelukast, Zafirlukast - mech

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7
Q

Antileukotriene that inhibits 5-lipoxygenase pathway

Blocks conversion of arachidonic acid to leukotrienes

A

Zileuton - mech

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8
Q

Asthma

A

Zileuton, Theophylline - use

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9
Q

Asthma - first line

A

Fluticasone, Budesonide - use

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10
Q

Asthma prophylaxis, long acting

A

Salmeterol, Formoterol - use

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11
Q

B2 agonist relaxes bronchial smooth muscle

A

Albuterol, Formoterol, Salmeterol - mech

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12
Q

Bronchial challenge test for asthma dx

A

Methacholine - use

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13
Q

Causes bronchodilation by inhibiting phosphodiesterase to increase cAMP levels due to decreased cAMP hydrolysis
Metabolized by CYP 450Blocks action of adenosin

A

Theophylline - mech

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14
Q

Direct vasodilatory effect on pulm and systemic arterial vascular beds
Inhibit platelet aggregation

A

Prostacyclin analogs (incl epoprostenol, iloprost) - mech

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15
Q

Disrupts disulfide bonds

A

N-acetylcysteine - mech

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16
Q

Far less sedating than 1st gen because decreased entry to CNS

A

Loratidine, Fexofenadine, Desloratadine - side fx

17
Q

Flushing

Jaw pain

A

Prostacyclin analogs (incl epoprostenol, iloprost) - side fx

18
Q

For aspirin-induced asthma

A

Montelukast, Zafirlukast - use

19
Q

For Pulm HTN: Decrease pulm vascular resistance

A

Endothelin receptor antagonists (incl. bosentan) - use

20
Q

Hepatotoxic

A

Zileuton - side fx

21
Q

Hepatotoxicity (LFT)

A

Endothelin receptor antagonists (incl. bosentan) - side fx

22
Q

HTN

A

Phenylephrine, Pseudoephedrine - side fx

23
Q

HTN

CNS stimulation/anxiety

A

Pseudoephedrine - side fx

24
Q

Inhibit cGMP PDE5 and prolong vasodilatory effect of NO

A

PDE-5 Inhibitors (incl sildenafil) - mech

25
Q

Inhibiting endothelin-1 receptor

A

Endothelin receptor antagonists (incl. bosentan) - mech

26
Q

M3 agonist

A

Methacholine - mech

27
Q

Monoclonal anti-IgE AB, binds unbound serum IgE and blocks binding to FcERI

A

Omalizumab - mech

28
Q

Mucolytic - loosen mucus plugs in CFAntidote for acetaminophen overdose

A

N-acetylcysteine - use (2)

29
Q

Muscarinic antagonist that blocks muscarinic receptor competitively

A

Ipratroprium - mech

30
Q

Narrow therapeutic window

A

Theophyilline - side fx

31
Q

Prevent bronchoconstriction in asthmaCOPD

A

Ipratroprium - use

32
Q

Pulm HTN

A

Prostacyclin analogs (incl epoprostenol, iloprost), PDE-5 inhibitors (sildenafil) - use

33
Q

Reduce hyperemia, edema, nasal congestion

Open obstructed Eustachian tubes

A

Pseudoephedrine, Phenylephrine - use

34
Q

Reversible inhibitors of H1 histamine receptor, 1st gen

A

Dipenhydramine, Chlorpheniramine, Dimenhydrinate - mech

35
Q

Reversible inhibitors of H1 histamine receptor, 2nd gen

A

Loratidine, Fexofenadine, Desloratadine - mech

36
Q

Sedation
Antimuscarinic
Anti-a-adrenergic

A

Dipenhydramine, Dimenhydrinate, Chlorpheniramine - side fx (3)

37
Q

Steroid
Inhibit synthesis of all cytokinesInactivate NF-KB, the transcription factor that induces production of TNF-a and other inflammatory agents

A

Fluticasone, Budesonide - mech

38
Q

Thins respiratory secretions, does not suppress cough reflex

A

Guaifenesin - use

39
Q

Tremor

Arrythmia

A

Salmeterol, Formoterol - side fx (2)

USMLE (23 decks)

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