Respiratory Drugs Reverse

Question 1

A agonists

Answer 1

Pseudoephedrine, Phenylephrine - mech

Question 2

Acute exacerbation of asthma

Answer 2

Albuterol - use

Question 3

Allergic asthma resistant to inhaled steroids and long-acting B2 agonists

Answer 3

Omalizumab - use

Question 4

Allergy

Answer 4

Loratidine, Fexofendaine, Desloratadine - use

Question 5

Allergy
Motion sickness
Sleep aid

Answer 5

Dipenhydramine, Dimenhydrinate, Chlorpheniramine - use

Question 6

Antileukotreine that blocks leukotriene receptors (CysLT1)

Answer 6

Montelukast, Zafirlukast - mech

Question 7

Antileukotriene that inhibits 5-lipoxygenase pathway

Blocks conversion of arachidonic acid to leukotrienes

Answer 7

Zileuton - mech

Question 8

Asthma

Answer 8

Zileuton, Theophylline - use

Question 9

Asthma - first line

Answer 9

Fluticasone, Budesonide - use

Question 10

Asthma prophylaxis, long acting

Answer 10

Salmeterol, Formoterol - use

Question 11

B2 agonist relaxes bronchial smooth muscle

Answer 11

Albuterol, Formoterol, Salmeterol - mech

Question 12

Bronchial challenge test for asthma dx

Answer 12

Methacholine - use

Question 13

Causes bronchodilation by inhibiting phosphodiesterase to increase cAMP levels due to decreased cAMP hydrolysis
Metabolized by CYP 450Blocks action of adenosin

Answer 13

Theophylline - mech

Question 14

Direct vasodilatory effect on pulm and systemic arterial vascular beds
Inhibit platelet aggregation

Answer 14

Prostacyclin analogs (incl epoprostenol, iloprost) - mech

Question 15

Disrupts disulfide bonds

Answer 15

N-acetylcysteine - mech

Question 16

Far less sedating than 1st gen because decreased entry to CNS

Answer 16

Loratidine, Fexofenadine, Desloratadine - side fx

Question 17

Flushing

Jaw pain

Answer 17

Prostacyclin analogs (incl epoprostenol, iloprost) - side fx

Question 18

For aspirin-induced asthma

Answer 18

Montelukast, Zafirlukast - use

Question 19

For Pulm HTN: Decrease pulm vascular resistance

Answer 19

Endothelin receptor antagonists (incl. bosentan) - use

Question 20

Hepatotoxic

Answer 20

Zileuton - side fx

Question 21

Hepatotoxicity (LFT)

Answer 21

Endothelin receptor antagonists (incl. bosentan) - side fx

Question 22

HTN

Answer 22

Phenylephrine, Pseudoephedrine - side fx

Question 23

HTN

CNS stimulation/anxiety

Answer 23

Pseudoephedrine - side fx

Question 24

Inhibit cGMP PDE5 and prolong vasodilatory effect of NO

Answer 24

PDE-5 Inhibitors (incl sildenafil) - mech

Question 25

Inhibiting endothelin-1 receptor

Answer 25

Endothelin receptor antagonists (incl. bosentan) - mech

Question 26

M3 agonist

Answer 26

Methacholine - mech

Question 27

Monoclonal anti-IgE AB, binds unbound serum IgE and blocks binding to FcERI

Answer 27

Omalizumab - mech

Question 28

Mucolytic - loosen mucus plugs in CFAntidote for acetaminophen overdose

Answer 28

N-acetylcysteine - use (2)

Question 29

Muscarinic antagonist that blocks muscarinic receptor competitively

Answer 29

Ipratroprium - mech

Question 30

Narrow therapeutic window

Answer 30

Theophyilline - side fx

Question 31

Prevent bronchoconstriction in asthmaCOPD

Answer 31

Ipratroprium - use

Question 32

Pulm HTN

Answer 32

Prostacyclin analogs (incl epoprostenol, iloprost), PDE-5 inhibitors (sildenafil) - use

Question 33

Reduce hyperemia, edema, nasal congestion | Open obstructed Eustachian tubes

Answer 33

Pseudoephedrine, Phenylephrine - use

Question 34

Reversible inhibitors of H1 histamine receptor, 1st gen

Answer 34

Dipenhydramine, Chlorpheniramine, Dimenhydrinate - mech

Question 35

Reversible inhibitors of H1 histamine receptor, 2nd gen

Answer 35

Loratidine, Fexofenadine, Desloratadine - mech

Question 36

Sedation Antimuscarinic Anti-a-adrenergic

Answer 36

Dipenhydramine, Dimenhydrinate, Chlorpheniramine - side fx (3)

Question 37

Steroid Inhibit synthesis of all cytokinesInactivate NF-KB, the transcription factor that induces production of TNF-a and other inflammatory agents

Answer 37

Fluticasone, Budesonide - mech

Question 38

Thins respiratory secretions, does not suppress cough reflex

Answer 38

Guaifenesin - use

Question 39

Tremor | Arrythmia

Answer 39

Salmeterol, Formoterol - side fx (2)