Respiratory drugs Flashcards
What are the 3 drug classes of bronchodilators?
Beta Adrenergic Agonists
Methylxanthines
Anticholinergics
Examples of beta adrenergic agonists
Metaproterenol (Alupent, Metaprel) --Neb, PO, MDI Albuterol (Proventil, Ventolin) --Neb, MDI, PO Terbutaline (Brethine) --Neb, PO, MDI, SC Salmeterol (Servent) --MDI
How do beta adrenergic agonists work?
stimulates beta receptors allowing smooth muscle relaxation
Examples of Methylxanthines
Theophylline (Theo-Dur)
–PO
Aminophylline (Truphylline)
–IV
How to methylxanthines work?
relaxes bronchial smooth muscles and improves contractility of diaphragm
Examples of anticholinergics
Ipratropium (Atrovent)
–Neb, MDI
How do anticholinergics work?
blocks action of acetylcholine resulting in bronchodilator
What are the 2 antiinflammatory drug classes?
Corticosteroid
Leukotriene receptor antagonist
Corticosteroid examples
Hydrocortisone (Solu-cortef) --IV Methylprednisolone (Solu-Medrol) --IV Prednisone --PO Beclomethasone (Vanceril) --MDI, nasal spray Fluticasone (Flovent) --MDI
Leukotriene receptor antagonist example
Montelukast (Singulair)
–PO
How do corticosteroids work for the respiratory system?
decreases inflammatory and immune responses
decrease edema in bronchial airways
decrease mucous secretion
How do leukotriene receptor antagonist work?
blocks the action of leukotrienes resulting in bronchodilator and anti-inflammatory effects
