Respiratory case examples Flashcards

1
Q

what happens in severe COPD?

A

decrease in FVC and FEV1 (more so)
ratio of FEV1:FVC decreases
hyperinflation limits inspiration
airway closure limits expiration

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2
Q

what causes reduced FVC and FEV1 to similar degrees and is treated by corticosteroids?

A

sarcoidosis

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3
Q

what is sarcoidosis ?

A

uncommon chronic inflammatory condition which produces granulomata in various tissues and organs, including skin, liver, lung, brain and heart
restrictive lung disease results from extensive deposition of inflammatory infiltrates

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4
Q

what are the symptoms of sarcoidosis?

A
fatigue and breathlessness and persistent cough
enlarged hilar lymph nodes
erythema nodosum 
plaques
maculopapular eruptions
subcutaneous nodules
lupus pernio
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5
Q

diagnosis of sarcoidosis

A

often difficult and may need lymph node biopsy

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6
Q

severe pulmonary fibrosis

A

decreased FVC and FEV1 to similar degrees so ratio remains unchanged . this is because the lungs cannot expand normally because of restriction

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7
Q

what is erythema nodosum

A

swollen fat under the skin causing red bumps and patches

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8
Q

why is asthma particularly troublesome at night?

A

allergens in bedroom
air is coldest
nasal secretions can drip into the chest
natural cortisol levels are lower

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9
Q

what drugs are in the brown inhaler?

A

steroid - to reduce inflammation

long acting Beta2 adrenoreceptor agonist - salmeterol

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10
Q

asthma

A

FVC unchanged
FEV1 decreased
ratio decreased

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11
Q

what are the features of nail clubbing?

A

softening of nail bed
loss of nail bed angle
increased convexity of nail fold
drumsticking of the finger distally

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12
Q

what conditions cause finger clubbing?

A
lung cancer
bronchiectasis 
lung abscess 
hypersensitivity
pneumonitis
CF
sarcoidosis
asbestosis
TB
congenital heart disease
Inflammatory bowel disease
cirrhosis
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13
Q

how does pulmonary fibrosis appear on a CT scan?

A

Ground glass/ broken glass appearance which do not clear with coughing

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14
Q

what does asbestos do?

A

causes fibrosis

and less commonly mesothelioma

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15
Q

what is a mesothelioma?

A

caused by asbestos exposure

rare and fatal tumour of pleura

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16
Q

what indicates severe lung disease?

A

home oxygen

17
Q

why are people with severe restrictive lung disease very thin?

A

increases work of breathing and causes calories deficit and weight loss

18
Q

what else causes restrictive lung disease?

A

non-muscular diseases of upper thorax e.g. kyphosis
obesity
diaphragm atic hernia
ascites

19
Q

how is TLco measured?

A

a fraction of CO will be transferred from alveoli to blood during max inspiration
how much diffused across alveolar membrane is compared against the predicted value