Respiratory - Cancer and ILD Flashcards

1
Q

risk factors for lung cancer?

A

smoking
asbestos
pollution
FHx

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2
Q

features of lung cancer?

A
cough
SOB
haemoptysis
weight loss
recurrent infections
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3
Q

most common type of cancer in smokers?

A

small cell carcinoma

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4
Q

what type of lung cancer causes hypercalcaemia?

A

squamous cell

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5
Q

what type of lung cancer causes SIADH?

A

small cell

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6
Q

what can locally invasive lung cancers cause?

A
pancoast tumour (affect brachial plexus)
SVC obstruction
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7
Q

what paraneoplastic syndromes can occur in lung cancer?

A

hypercalcaemia (PTH mimic)
hyponatraemia (ADH mimic)
eaton lambert syndrome (MG mimic)
high ACTH (cushing’s syndrome)

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8
Q

what can small cell tumours sometimes produce? investigation done?

A

ACTH

no suppression by the dexamethasone suppression test

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9
Q

investigations for lung cancer?

A

CXR
CT scan
PET scan

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10
Q

which lung cancer has the worst prognosis?

A

small cell

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11
Q

risk factors for asbestos lung disease?

A

smoking (synergistic)
exposure
length of exposure

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12
Q

what spectrum of disease can asbestos cause?

A
benign plaques
pleuritis
pleural effusion
pulmonary fibrosis
malignant mesothelioma
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13
Q

features of PF?

A
SOB
dry cough
clubbing 
cyanosis
CO2 retention
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14
Q

investigations for PF?

A

PFT (reduced, FVC, FEV1/FVC >70)
ABGs
CXR
High resolution CT

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15
Q

examples of EAA? causes?

A

farmer’s lung = bacteria
bird fanciers = avian protein
malt workers = fungi

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16
Q

treatment of EAA?

A

avoid allergen

steroids

17
Q

what type of hypersensitivity is EAA?

A
Type III (immune complex)
and
Type IV (cell mediated)
18
Q

CXR of pulmonary fibrosis shows?

A

lower lobe shadowing

19
Q

what is caplan’s syndrome? features?

A

RA + Pneumoconiosis

pulmonary nodules

20
Q

what can 15-20yrs of quarts exposure lead to?

A

silicosis

21
Q

silicosis on CXR shows?

A

egg cell calcification of hilar nodes

22
Q

what drugs can cause ILD?

A

amiodarone
MTX
nitrofurantoin

23
Q

what type of lung cancer usually produces PTH?

A

squamous

24
Q

what type of lung cancer is often found peripheral and central?

A

peripheral - adeno

central - squamous