Respiratory - Cancer and ILD Flashcards
risk factors for lung cancer?
smoking
asbestos
pollution
FHx
features of lung cancer?
cough SOB haemoptysis weight loss recurrent infections
most common type of cancer in smokers?
small cell carcinoma
what type of lung cancer causes hypercalcaemia?
squamous cell
what type of lung cancer causes SIADH?
small cell
what can locally invasive lung cancers cause?
pancoast tumour (affect brachial plexus) SVC obstruction
what paraneoplastic syndromes can occur in lung cancer?
hypercalcaemia (PTH mimic)
hyponatraemia (ADH mimic)
eaton lambert syndrome (MG mimic)
high ACTH (cushing’s syndrome)
what can small cell tumours sometimes produce? investigation done?
ACTH
no suppression by the dexamethasone suppression test
investigations for lung cancer?
CXR
CT scan
PET scan
which lung cancer has the worst prognosis?
small cell
risk factors for asbestos lung disease?
smoking (synergistic)
exposure
length of exposure
what spectrum of disease can asbestos cause?
benign plaques pleuritis pleural effusion pulmonary fibrosis malignant mesothelioma
features of PF?
SOB dry cough clubbing cyanosis CO2 retention
investigations for PF?
PFT (reduced, FVC, FEV1/FVC >70)
ABGs
CXR
High resolution CT
examples of EAA? causes?
farmer’s lung = bacteria
bird fanciers = avian protein
malt workers = fungi
treatment of EAA?
avoid allergen
steroids
what type of hypersensitivity is EAA?
Type III (immune complex) and Type IV (cell mediated)
CXR of pulmonary fibrosis shows?
lower lobe shadowing
what is caplan’s syndrome? features?
RA + Pneumoconiosis
pulmonary nodules
what can 15-20yrs of quarts exposure lead to?
silicosis
silicosis on CXR shows?
egg cell calcification of hilar nodes
what drugs can cause ILD?
amiodarone
MTX
nitrofurantoin
what type of lung cancer usually produces PTH?
squamous
what type of lung cancer is often found peripheral and central?
peripheral - adeno
central - squamous