Respiratory Flashcards
What is the most common organism in bronchiectasis?
H. Influenzae
What are the causes of upper lobe fibrosis?
CHARTS
Coal workers ppeumoconiosis
Histiocytosis
Ankylosing spondylitis/allergic bronchopulmonary aspergillosis
Radiation
Tuberculosis
Silicosis, sarcoidosis
What are the spirometry findings in pulmonary fibrosis?
Reduced FVC, normal fev1/fvc
What is the second line investigation for asthma if spirometry is normal?
Fraction of exhaled nitrous oxide testing
FeNO
What medication causes lower zone lung fibrosis?
Amiodarone (and bleomycin, methotrexate)
What are the features of acute sarcoidosis?
Erythema nodosum
Bilateral hilar lymphadenopathy
Swinging fever
Polyarthralgia
What investigations are required before starting azithromycin?
ECG (and LFTs)
What is first line mgt of COPD?
SABA or SAMA PRN
What is the second line mgt of COPD?
Asthmatic features/steroid responsiveness: LABA and ICS
NO asthmatic features - LABA and LAMA (if on SAMA switch to SABA)
what is the investigation of choice for idiopathic pulmonary fibrosis?
high res CT
what are the features of kartagener’s syndrome?
dextrocardia
bronchiectasis
recurrrent sinusitis
subfertility
in step down tx of asthma, what reduction of corticosteroid tx are you aiming for?
25-50%
most common pathogens causing IECOPD?
haemophilus influenzae
strep pneumoniae
moraxella catarrhalis
investigation of pleural effusion?
PA CXR
US guided pleural aspiration (sent for pH, protein, LDH, cytology and microbiology)
contrast CT to investigate underlying cause
how to differentiate transudate and exudate in pleural effusion?
exudate if: pleural fluid protein/serum protein >0.5
pleural fluid LDH / serum LDH >0.6
pleural fluid LDH more than two thirds the upper limits of normal serum LDH