Resp - Lung cancer Flashcards
Lung Cancer
Histological subtypes
Comparison between SCLC and NSCLC
SCLC (5-10%)
NSCLC:
- Large cell carcinoma (5-10%)
- Adenocarcinoma (45-55%)
- Squamous cell carcinoma (20-30%)
Lung cancer
Route of spread
Lung Cancer
Epidemiology
Lung Cancer
Reasons of high lung cancer prevalence in Asian female non-smokers
Lung Cancer
Causes
Lung cancer
Pathogenesis
Lung Cancer
Key genetic mutations
Lung Cancer
Local symptoms
Lung Cancer
Paraneoplastic syndrome
Lung Cancer
Systemic syndromes
Lung Cancer
P/E
Lung Cancer
Biochemical Ix
Lung Cancer
Radiological Ix
Lung Cancer
Genetic testing
- Rationale
- Indications
- Common mutations
- Timing for testing
- Sample collection
Lung Cancer
Genetic testing pitfalls
Lung Cancer
Outline treatment options for diff. histological subtypes
Targeted therapy options for NSCLC
Lung cancer
Medical treatment options: chemotherapy and targeted therapy
Lung cancer
Immunotherapy options
causes of hyponatremia in CA lung patients
Syndrome of inappropriate ADH (Most common)
Depletional hyponatremia due to poor oral intake
Cortisol insufficiency due to bilateral adrenal metastasis
Treatment of lung cancer brain metastasis
Secondary lung tumour
Source of tumour/ common primaries
Imaging feature
Management
Lymphangitis carcinomatosis
Common primaries
Imaging
Management
SCLC
Treatment for limited stage disease, unresectable stage disease and extensive stage disease
EGFR actionable mutations (exon 19 deletion, L858R mutation) lung cancer
Treatment options
Side effects
Resistance pattern
ALK translocation/ ROS1 rearrangement lung cancer
Treatment option
Side effects
Resistance pattern
PD-LI expression lung cancer
Treatment option
Side effect
NSCLC
Treatment outline
Lung Cancer
Surgical treatment option for resectable NSCLC
Lung Cancer
Criteria for resectable NSCLC
Lung cancer
Tissue diagnosis methods
Lung cancer
Radiological presentations
