CNS - Meningitis, encephalitis, brain abscess Flashcards
Meningitis
Classification
Meningitis vs encephalitis
Distinguishing feature
Bacterial meningitis
Common causative pathogens
Bacterial meningitis
Most likely causative organism across age groups and demographics
Viral meningitis
Most common pathogens
Subacute and malignant meningitis
Causes
Bacterial meningitis
Pathophysiology
Viral meningitis
Pathophysiology
Meningitis
S/S
Meningitis
History taking questions
Meningitis
P/E
Meningitis
Biochemical Ix
Microbiological Ix:
- Blood culture
- CSF analysis by lumbar puncture; CSF smear, culture with sensitivity testing, antigen detection and PCR
- Blood and urine for viral culture and PCR
- Throat, rectal swabs for viral culture and PCR
- Serology
Meningitis
Compare CSF parameters between bacterial vs viral vs fungal infection
Meningitis
Microbiological workup
Blood culture
* Cultures should be obtained before administration of antimicrobials
* Useful when lumbar puncture is delayed or deferred due to increased ICP
Meningitis
Radiological Ix