research methods (brain imaging) Flashcards
what are the 5 kinds of brain imaging?
MRI
MEG
fNIRS
EEG
PET
how many kinds of MRI are there?
- sMRI
- fMRI
- dMRI
what does the number in a voxel represent?
the bigger the number, the ___________ the voxel
voxel intensity; brighter
which of the 3 MRIs is also known as T1-weighted imaging?
sMRI
sMRI is primarily used to study ____ whereas dMRI is used to study _____-related microstructure.
GM; WM
what are the 2 measurements in dMRI?
- FA (fractional anisotropy)
- MD (mean diffusivity)
what do FA and MD images show? where are they from?
from raw dMRI images.
- FA shows direction of water movements in WM
- MD shows overall amount of water diffusion/movement in WM
high/low levels of FA indicates compromised microstuctural integrity. why?
low.
water movement in WM is highly directional, so should be high FA. Low FA in WM indicates compromised microstural integrity.
*FA highest in WM, low in GM, lowest in ventricles/CSF
high/low levels of MD indicates compromised microstuctural integrity. why?
high.
MD is non-directional. Lowest in WM, high in GM, highest in ventricles/CSF.
what does fMRI measure?
brain activity from GM regions
- measures blood-oxygen-level-dependent (BOLD) activity
- changes in deoxyhemoglobin driven by localised changes in brain blood flow and blood oxygenation
during fMRI scan, multiple brain volumes are acquired across short intervals (from ___ to ____).
duration of these intervals: _______________
0.7s-3s; temporal resolution
fMRI analyses always involve a constrast between 2 conditions only. cannot be more or less.
true or false?
false. at least 2.
the 2 basic conditions of an fMRI study are?
what is the point of the control?
- control task - act as baseline activation level, to compare to activity in the task of interest, as everyone has different baseline activation levels.
- task of interest
what does EEG stand for?
electroencephalogram
what does EEG (electroencephalogram) measure?
electrical activity in the brain during a very brief event