Reproductive Pathophysiolgy Female II Flashcards
what can uterine endometrial cysts in horses be confused with?
early embryo
how can you diagnose a uterine endometrial cyst in a horse?
ultrasound: cyst will remain in same position while embryo will change position
what mares are more likely to have uterine endometrial cysts?
older mares
what are uterine tumors: benign polyps?
spherical protrusions into the uterus
what species get uterine benign polyps?
cats
dogs
rats
mice
what species are uterine adenocarcinomas common in?
rabbits
cattle
what percentage of does (female rabbits) get adenocarcinoma?
60% of those over 4 years old
where can adenocarcinoma metastasize?
liver
lungs
what species are uterine lymphosarcoma common in?
ruminants
what does the uterus look like in uterine lymphosarcoma?
thickened with multiple masses
what is uterine lymphosarcoma caused by?
bovine leukosis virus
what can you use a blood smear for in uterine lymphosarcoma?
to look for atypical or immature lymphocytes
who is uterine leiomyoma/leiomyosarcoma most common in?
dogs and cats >10 years
what is uterine leiomyoma/leiomyosarcoma caused by?
estrogen stimulation
what is endometritis?
inflammation of the endometrium
what is metritis?
inflammation of endometrium and myometrium
what are some findings in nonspecific endometritis/metritis?
purulent exudates
neutrophils
lymphocytes and plasma cells in endometrial stroma
when is nonspecific endometritis/metritis seen in ruminants?
after difficult parturitions
what can severe cases of nonspecific endometritis/metritis lead to?
infertility
when can organisms in metritis/pyometra be introduced in cattle?
during calving
another systemic disease
during mating
what are two organisms implicated in metritis/pyometra in cattle after mating?
Campylobacter fetus
Tritrichimonas foetus
when is Tritrichomonas foetus most commonly seen?
postcoital pyometra
when is brucellosis transmitted?
mating
what causes brucellosis in cattle?
Brucella abortus
what causes brucellosis in swine?
Brucella suis
what causes contagious equine metritis?
Taylorella equigenitalis
how is contagious equine metritis transmitted?
coitus
what does contagious equine metritis cause?
infertility/abortions
mucopurulent vaginal discharge
what is pyometra?
acute or chronic suppuration inflammation of the uterus
what species is pyometra seen commonly in?
bitch
queen
cow
mare
what is bacterial endometritis that leads to pyometra from?
progesterone stimulation: prolonged
what is pyometra in cats and dogs from?
cystic endometrial hyperplasia: pyometra complex
prolonged progesterone stimulation
what is pyometra from in cattle?
progesterone stimulation from persistent corpus luteum
what is pyometra from in mares?
postpartum
post coitus
persistent CL is not necessary
what is fetal mummification like?
sterile
leathery appearance
what is fetal maceration like?
uterine infection causes
necrosis and autolysis of fetus
tissue emphysema possible
what do endometrial cups in equine induce?
accessory corpus luteum
where are amniotic plaques found?
inner amnion
where are calcium deposits found?
amnion and allantois
what do calcium deposits look like?
white streaks
flecks
who is hydramnios and hydrallantois seen in?
cows
mares
what is hydramnios?
excess fluid in amniotic sac
what is hydrallantois?
excess fluid in allantoic sac
what are some complications of hydramnios and hydrallantois?
uterine atony
retained fetal membranes
metritis
dangerous to dam to remove fluid quickly
who does adventitious placentation occur in?
ruminants
what can adventitious placentation be related to?
hydrallantois
when does postpartum involution occur in the dog?
12 weeks
how long can a dog have serosanguinous discharge postpartum?
4-6 weeks
how long does postpartum involution take in the cow?
6 weeks
how long does postpartum involution take in the mare?
as little as 9 days
who does does retained fetal membranes usually occur in?
cows
what is the etiology of retained fetal membranes in cows?
infection
hormone imbalance
dystocia
low calcium
what is subinvolution of placental sites?
rare, dogs
invasion of trophoblasts to endometrium at placental sites
persistent hemorrhagic discharge
is brucella zoonotic?
yes
what does Brucella abortus colonize?
lymph nodes
how is Brucella abortus transmitted?
contaminated tissues/exudates
what do the lesions of Brucella abortus affect?
placenta and fetus
how is Brucella suis transmitted?
coitus
how can infected boars transmit Brucella suis?
semen
what does Brucella suis cause?
late abortions
stillbirths
retained fetal membranes
what is abortion due to Brucella in small ruminants due to?
sheep: Brucella ovis
goats: Brucella melitensis
what can Brucella canis cause in male dogs?
orchitis
epididymitis
what does Brucella canis cause postpartum?
gray-green vaginal discharge for several weeks
do cats have a natural Brucella strain?
no- can be infected but rare
is Campylobacter zoonotic?
yes
what Campylobacter impacts cattle?
Campylobacter fetus var. venerealis
what is the most common abortifacient in sheep where brucellosis is controlled?
Campylobacter
what can Campylobacter cause in 40% of abortions in sheep?
orange-yellow necrotic foci in the fetus liver
1-2 cm in diameter
is Listeria zoonotic?
yes
how is Listeria spread to ruminants?
ingestion
what can you see in near term aborted fetuses with Listeria?
pin point yellow white foci of necrosis in liver and spleen
what is the most common abortifacient in goats where brucellosis is controlled?
Chlamydia
is Chlamydia zoonotic?
yes
how does Chlamydia present in goats and sheep?
cyclic nature in herd
initial high abortion
then new outbreak
can be chronic
what causes Q fever in ruminants?
Coxiella burnetti
what can Coxiella burnetti cause in humans?
pneumonia
cardiac issue
how can animals get Coxiella burnetti?
contaminated dust
what is the most common cause of mycotic abortion?
Aspergillosis
what type of outbreaks does mycotic abortion cause?
sporadic
is Toxoplasmosis zoonotic?
yes
who is Toxoplasmosis seen in?
sheep and goats
what are the cotyledons like in Toxoplasmosis?
bright red with small white foci
who does Tritrichomonas impact?
cattle
how can you identify herpes reproductive infections?
focal areas of necrosis with “owl-eye” eosinophilic intranuclear inclusion bodies
what does herpes equi-1 cause?
equine rhinopneumonitis
what causes equine coital exanthema?
herpesvirus equi-3
what causes infectious bovine rhinotracheitis (IBR)?
herpesvirus bovis-1
when does herepesvirus bovis-1 cause abortion?
second half of gestation
what does porcine herpesvirus-1 cause?
pseudorabies
mummified fetuses, late abortions, stillbirths
what does porcine herpesvirus 1 cause in non-swine?
fatal: intense pruritis
what does herpesvirus canis cause?
mild respiratory infection in adults
neonatal mortality in pups
what causes feline rhinotracheitis?
feline herpesvirus 1
what does equine arteritis virus cause?
mild respiratory infection
arthritis in placenta
what type of abortions does swine infertility and respiratory syndrome cause?
mix of stillborn, mummified fetuses, and weak piglets
what does porcine parvovirus cause?
stillbirth
mummification
embryonic death
when is there no abortion with porcine parvovirus?
after 70 days fetuses are resistant
how is epizootic bovine abortion spread?
tick borne
what are mammary gland tumors in dogs related to?
hormonal factors: progesterone and estrogen
how many mammary gland tumors in dogs are malignant?
50%
what type of tumors are mammary gland tumors in dogs?
adenocarcinoma
what is mastitis related to?
late pregnancy/birth
pseudopregnancy
clinically ill
what type of cancer can look just like mastitis?
inflammatory carcinoma
what are some malignant mammary tumors seen in dogs?
adenocarcinomas
malignant mixed cell tumors
inflammatory carcinoma
who do mammary gland tumors occur in?
dogs and cats
what are benign mammary gland tumors like in dogs and cats?
small and smooth
slow growing
freely moveable
what can make a mammary tumor in a dog a better prognosis?
small size
clean margins
what percent of mammary gland tumors in cats are malignant?
80%
what is fibroadenomarous hyperplasia?
benign non-neoplastic mammary condition in cats
what is fibroadenomatous hyperplasia dependent upon?
progesterone
what can mouse mammary tumors be induced by?
retrovirus
mouse mammary tumor virus
what does Campylobacter fetus look like?
gram negative bacillus
what does Tritrichomonas foetus look like?
flagellated protozoa
how can Tritrichomonas foetus be identified?
smear of vaginal discharge
where can you culture contagious equine metritis from?
clitoral fossa
uterine endometrium
cervix
in whom is pyometra rare?
small ruminants
when are equine endometrial cups seen?
days 35-100-120
what makes up amniotic plaques?
squamous epithelium
is hydramnios a fetal or placental problem?
fetal
is hydramnios or hydrallantois more common?
hydrallantois
when does Brucella abortus cause abortion?
7-9 months to term
what does Brucella suis cause?
late abortions
stillbirths
retained fetal membranes
is the non-gravid small ruminant uterus resistant to Brucella infection?
yes
what is Listeria usually associated with?
encephalitis
when does Herpes equi-1 cause abortions?
9-10 months of gestation
when do puppies infected in utero with Herpesvirus canis die?
usually within 10 days of birth
can mammary gland tumors be seen in spayed cats?
yes