Reproductive Endocrinology

Question 1

What is the order of changes that occur during puberty?

Answer 1

Accelerated growth ➡️ Telarche ➡️
Pubarche ➡️ Menarche

Question 2

What is the definition of precocious puberty?

Answer 2

Pubarche or Telarche <7 years of age ( Caucasian)
or <6 years of age ( African American)

Question 3

What is the definition of delayed puberty ?

Answer 3

Absent or incomplete breast development by 12 years

Question 4

What structure is responsible for the production of progesterone after ovulation and before menstruation?

Answer 4

Corpus luteum

Question 5

Estrogen synthesis is based on what theory?

Answer 5

Two-cell theory or
Two cell , Two gonadotropin Theory

Question 6

If fertilization occurs, what hormone produced by the developing trophoblast maintains corpus luteum?

Answer 6

Human chorionic gonadotropin

Question 7

Average age of menarche ?

Answer 7

12-13 years of age

Question 8

Most common central cause of Precocious Puberty?

Answer 8

Idiopathic

Question 9

Sensitive marker of ovarian follicle competence?

Answer 9

Inhibin

Question 10

Results in the initiation of LH surge in women?

Answer 10

Puberty

Question 11

Characteristics of follicular growth? (3)

Answer 11

1. Maximal number of oocytes occur 16-29 weeks age of pregnancy.
2. Most rapid decrease of oocytes occur before birth.
3. Two million oocytes at birth will decrease to 300,000 at puberty

Question 12

Age wherein precocious puberty development is considered?

Answer 12

7.5 years old

Question 13

Major determinant of cycle length ?

Answer 13

Follicular phase

Question 14

Which element when it deposits in the pituitary may result in the destruction of cells producing LH and FSH ?

Answer 14

Iron

Question 15

What type of cervical mucus indicates a women has ovulated?

Answer 15

Thin

Question 16

Which specific hormone peaks in the plasma as circulating FSH rise?

Answer 16

Estradiol