Hypertensive Disease Of Pregnancy Flashcards
What is the definition of gestational hypertension?
SBP >/= 140 and DBP >/=90 on two occasions at least 4 hours apart after 20 weeks gestation in women with previously normal BP.
What percentage of patients with preeclampsia with severe features develop HELLP syndrome?
10%
What are the components of HELLP Syndrome?
Hemolysis
Elevated Liver enzymes
Low platelets
When should you deliver in a patient with with preeclampsia without severe features ?
37 weeks
When should you deliver in a patient with with preeclampsia with severe features ?
34 weeks
What is eclampsia?
Grand mal seizures in a preeclamptic patient with no other cause.
What is the serum concentration of MgSO4 used in therapeutic seizure prophylaxis?
4.8 -8.4 mg/mL
What is the serum concentration of MgSO4 used in therapeutic seizure prophylaxis?
4.8 -8.4 mg/mL
What should you administer in cases of MgSO4 overdose?
10ml 10% Calcium chloride or
Calcium gluconate IV
Case of G1P0 on 39 weeks AOG with BP 160/90, with second reading 150/100, negative urine protein and no other symptoms. What is the diagnosis?
Gestational Hypertension
Most practical way to measure MgSO4 Toxicity?
Patellar Reflex
Blood product to be transfused in a patient with massive hemorrhage?
Whole blood
Which is true about conforming elevated blood pressure during pregnancy?
Patient should be seated when blood pressure is taken on 2 occasions 4-6hrs apart.
Which simple laboratory test you request to help diagnose possible preeclampsia?
Urine protein
If the mean blood pressure of the patient is 148/96 mmHg after repeat measurements , what is the possible diagnosis of the patient?
Mild preeclampsia
What is the ideal increase in weight for the patient per week during this period of her pregnancy?
1 lb
Diagnosis of severe preeclampsia? (10)
- SBP >/= 160 mmHg
- DBP >110mmHg
- Thrombocytopenia
- Oliguria <500ml / 24 hrs
- Elevated serum Creatinine
- RUQ pain
- AST ALT elevation
- Headache , visual changes
- Fetal IUGR
- DIC
Accepted pathophysiology of preeclampsia?
Generalized arteriolar constriction
Primary goal of treatment for preeclampsia?
Prevention of seizures
Magnesium sulfate 4g loading dose and 2g maintenance
Risk factors for preeclampsia?
- Chronic hypertension, Renal diseases , Collagen Vascular Disease, Diabetes
- Nulliparity , previous preeclampsia, multiple gestational, abnormal placentation
- Female relatives of parturient with preeclampsia
Abnormal findings in HELLP Syndrome?
Hemolysis
Elevated liver enzymes
Low platelets
What percentage of neonatal death can occur with HELLP Syndrome?
20-25%
Diagnosis of gestational hypertension?
BP above 140/90 on at least two occasions taken 4-6 hours apart while patient is seated.