Repro Flashcards
Cystic swelling of chorionic villi and proliferation of chorionic epithelium (trophoblasts);
hydatidiform mole
vaginal bleeding, uterine enlargement more than expected, pelvic pressure/pain:
hydatidiform mole
associated with bHCG mediated sequelae–early preeclampsia, lheca-lutein cysts, hyperemesis gravidum, hyperthyroidism:
hydatidiform mole
Tx of hydatidiform mole:
D&C and methotrexate; monitor bHCG
46 XX, 46 XY
complete mole
enucleated egg + 1 sperm (duplicated paternal DNA)
complete mole
contains NO fetal parts
complete mole
increase uterine size
complete mole
super high bHCG
complete mole
“honey combed uterus”, “cluster of grapes”, “snowstorm pattern on US”
complete mole
15-20% risk of malignancy:
complete mole
2% risk of choriocarcinoma
complete mole
69, XXX, 69 XXY, 69 XYY
partial mole
2 sperm + 1 egg
partial mole
contains fetal tissue
partial mole
no increase in uterine size
partial mole
moderate increase in bHCG:
partial mole
fetal parts on imaging
partial mole
<5% risk of malignancy
partial mole
rare risk of choriocarcinoma
partial mole
malignancy of trophoblastic tissue (cytotrophoblasts and syncytiotrophoblasts)
choriocarcinoma
no chorioninc villi present:
choriocarcinoma
increased frequency of BL.multiple theca-lutein cysts
choriocarcinoma
abnormally increase bHCG, SOB, hemoptysis
choriocarcinoma
