Ovarian Tumors

Question 1

Most common ovarian neoplasm:

Answer 1

serous cystadenoma

Question 2

Histo of serous cystadenoma:

Answer 2

Lined with tube-like epithelium; often BL

Question 3

Appearance of mucinous cystadenoma:

Answer 3

multiloculated, large, lined by mucus secreting epithelium

Question 4

Endometrioma:

Answer 4

endometriosis within ovary with cyst formation

Question 5

Sx of and endometrioma:

Answer 5

pelvic pain, dysmenorrhea, dyspareunia, sx vary with menstrual cycle

Question 6

Appearance of endometrioma:

Answer 6

chocolate cyst
endometrioma filled with dark, reddish brown blood
seen as a complex mass on ultrasound

Question 7

What do endometriomas do during menses:

Answer 7

get larger d/t cyclic bleeding

Question 8

Mature cystic teratoma: benign or malignant?

Answer 8

benign

Question 9

Most common ovarian tumor in females 10-30 y/o

Answer 9

mature cystic teratoma

Question 10

Elements of a mature cystic teratoma:

Answer 10

elements from all 3 germ layers (teeth, hair, sebum)

Question 11

Teratome with functional thyroid tissue:

Answer 11

struma ovarii

Question 12

AE of a mature cystic teratoma:

Answer 12

can present with pain d/t enlargement or torsion

Question 13

Histo of fibroma:

Answer 13

bundles of spindle shaped fibroblasts

Question 14

Meig’s syndrome:

Answer 14

triad of ovarian fibroma, ascites, and hydrothorax (pleural effusion)

Question 15

Thecoma

Answer 15

produces estrogen–presents as abnormal uterine bleeding in post menopausal females

Question 16

Brenner tumor histo

Answer 16

resembles bladder epithelium (transitional cell tumor); coffee bean nuclei

Question 17

Gross appearance of brenner tumor:

Answer 17

solid, pale, tan-yellow tumor

Question 18

Most common malignant ovarian neoplasm:

Answer 18

serous cystadenocarcinoma

Question 19

Special characteristic seen in serou cystadenocarcinoma:

Answer 19

psamomma bodies

Question 20

Rare, malignant mucinous ovarian epithelial tumor:

Answer 20

mucinous cystadenocarcinoma

Question 21

What is pseudomyxoma peritonei? And what is it associated with?

Answer 21

intraperitoneal accumulation of mucinous material

associated with mucinous cystadenocarcinoma

Question 22

Most common malignant ovarian neoplasm in children?

Answer 22

dysgerminoma

Question 23

Dysgerminoma histo:

Answer 23

fried egg cells

Question 24

Dysgerminoma tumor markers:

Answer 24

hCG, LDH

Question 25

Aggressive ovarian tumor containing fetal tissue and neuroectoderm most commonly diagnose before age 20?

Answer 25

immature teratoma

Question 26

Yolk Sac tumor marker:

Answer 26

AFP

Question 27

Yolk Sac tumor histo:

Answer 27

Schiller-Duval bodies

Question 28

Location of yolk sac tumor

Answer 28

ovaries, testes, and sacrococcygeal area in young children

Question 29

Most common malignant stromal tumor:

Answer 29

Granulosa cell tumor

Question 30

What do granulosa cell tumors produce?

Answer 30

estrogen and progesterone

Question 31

S/sx of granulosa cell tumor:

Answer 31

post menopausal bleeding, sexual precocity (in pre-adolescents), breast tenderness

Question 32

Granulose cell tumor histo:

Answer 32

Call-Exner bodies--granulosa cells arranged haphazardly around collections of eosinophilic fluid

Question 33

Krukenberg tumor:

Answer 33

GI malignancy that metastasizes to the ovaries (mucin-secreting signet cell adenocarcimona of the stomach bilateral

Question 34

the worst gynecological cancer prognosis and the most common cause of cancer death from gynecological tumors

Answer 34

ovarian carcinoma