Immuno Cells and Cytokines Flashcards
1
Q
CD3
TCR–binds Ag-MHC complex
CD28–binds B7 on APC
A
T cell markers
2
Q
CD3 TCR CD28 CD4 CD40L CXCR4/CCR5 (co-receptor for HIV)
A
Th cell markers
3
Q
CD3
CD8
TCR
CD28
A
Cytotoxic T cell markers:
4
Q
CD3
CD4
CD28 TCR
CD25
A
Reg Cell markers:
5
Q
Ig CD 19, CD20, CD21 (receptor for EBV) CD40 MHC II B7:
A
B cell markers
6
Q
CD14 CD40 CCR5 MHC II, B7 (CD80/86) Fc and C3b receptors (enhanced phagocytosis)
A
Macrophage cell markers
7
Q
CD16
CD56 (suggestive marker for NK cells)
A
NK cell markers
8
Q
Hematopoietic stem cell marker:
A
CD34
9
Q
CD117 and CD 25
A
mast cell markers
10
Q
induces T cell differentiation into Th1 cells and activates NK cells
A
IL-12
11
Q
activates endothelium, causes WBC recruitment, vascular leak
A
TNF-a
12
Q
causes cachexia in malignancy
A
TNF-a
13
Q
maintains granuloma in TB
A
TNF-a
14
Q
mediates fever and sepsis
A
IL-1, IL-6, TNF-a
15
Q
stimulates macrophages to kill phagocytosed pathogens
A
IFN-gamma
