Repeat Qs

Question 1

Pt treated with an antidiabetic drug that prevents the breakdown of hormones. Which of the following side effects would you expect?
A. Hypoglycemia
B. Infections
C. Acute kidney injury
D. Heart failure

Answer 1

INFECTIONS

Question 2

Pt with T2D brought to ER complaining of tachycardia, shaking, sweating, dizziness, nausea, and vomiting. Which of the following drugs was he most likely treated with?
A. Canagliflozin
B. Glyburide
C. Metformin
D. Pioglitazone

Answer 2

GLYBURIDE

Question 3

Results of annual check up of T2D pt revealed weight gain and decrease bone mineral density. What is the target of the drug?

Answer 3

= TZDs = NUCLEAR RECEPTOR

Question 4

Which of the following MOA of drugs likely will cause weight gain?
A. xSGLT2
B. xK Ch
C. xDPP4
D. GLP1 agonist

Answer 4

IDES = Inhibition of K+ channels

Question 5

Which of the following immunosuppressive drugs target a phosphatase that is responsible for the activation of a transcription factor?
A. Azathioprine
B. Basiliximab
C. Sirolimus
D. Tacrolimus

Answer 5

Tacrolimus

Question 6

Which of the following drugs is indicated for the treatment of osteoporosis and acts on a G-protein coupled receptor?
A. Alendronate
B. Calcitonin
C. Calcitriol
D. Raloxifene

Answer 6

Calcitonin

NIN

Question 7

Which of the following drugs inhibits an enzyme in the in the membrane of thyroid follicular cells?
A. Methimazole
B. Desiccated thyroid
C. Levothyroxine
D. Letrozole

Answer 7

Methimazole

Question 8

Pt on CYP34 inhibitors, needs TX with antiplatelet drug. Which would you recommend?
A. UFH
B. Warfarin
C. Clopidogrel
D. Dabigatran
E. Rivaroxaban
F. Aspirin

Answer 8

ASPIRIN

Question 9

Drug causing purple toe syndrome as an AE also has which other AE?
A. Hepa
B. HTN
C. Neuropathy
D. Teratogenicity
E. Thrombocytopenia

Answer 9

Teratogenicity

Question 10

How Prednisone Affects IL2(cytokines)

Answer 10

Inhibit, diminish production of cytokines, inhibit action

Question 11

Target Organs
1. Canagliflozin
2. Exenatide
3. Glipizide
4. Insulin

Answer 11

1. Kidney
2. Brain, B cell, GIT
3. B cell
4. SKM, Liver, AT

Question 12

HYPOTHYROIDISM SX

Answer 12

-Low HR/HF/Low BP
-Constipation
-Muscle pain/fat/weak
-Brittle or dry hair/nails
-Weight gain, low temp

Question 13

HYPERTHYROIDISM SX

Answer 13

-High HR/Palp/High BP
-Diarrhea
-Low bone mineral density
-Hair loss, SWEAT, itchy, flush, bruise
-Weight loss, high temp