Random Stuff

Question 1

Purple toe syndrome

Answer 1

Warfarin

Question 2

Drugs that lower TGs the most

Answer 2

Niacin (answer), statins, fibrates

Question 3

BPH drug

Answer 3

Finasteride (and dutasteride)

Question 4

Most androgenic

Answer 4

Norgestrel (answer) and levonorgestrel

Question 5

NK Cell stuff

Answer 5

Rituximab

Question 6

Belatacept MOA and Indication

Answer 6

CTLA-4 binds to B7, prevents T cell activation via CD28 (signal 2)

USE: Organ transplant rejection prophylaxis

Question 7

What Natalizumab acts on

Answer 7

Effector T cell

Question 8

Antidiabetic causes weight gain and bone loss

Answer 8

TZD / GLITAZONES

Question 9

What organ does TZD act on

Answer 9

Liver / SKM

Question 10

Drug not reversed by Protamine

Answer 10

Fondaparinux

Question 11

Methimazole vs Propylthiouracil

Answer 11

BOTH: inhibit thyroid peroxidase (TPO)

ONLY PTU: inhibits peripheral T4 to T3 conversion by 5’ deiodinase

Question 12

Pt is picking up thyroid medication that targets a nuclear receptor. Which of these pts is taking a dose that is too low?

Answer 12

Being treated for HYPOthyroidism

dose too low = sx of hypothyroidism

-Low HR/HF/Low BP
-Constipation
-Muscle pain/fat/weak
-Brittle or dry hair/nails
-Weight gain, low temp

Question 13

Pt picking up thyroid medication that targets an enzyme. Which of these pts is taking a dose that is too low?

Answer 13

Being treated for HYPERthyroidism

dose too low = sx of hyperthyroidism

-High HR/Palp/High BP
-Diarrhea
-Low bone mineral density
-Hair loss, SWEAT, itchy, flush, bruise
-Weight loss, high temp

Question 14

Drug that inhibits calcitonin / calcitonin MOA?

Answer 14

acting on G-protein coupled receptor

Question 15

What does PTH act on

Answer 15

Osteoblasts with a BBBB

Question 16

Requires neg TB

Answer 16

TNF (inflix and ada)

Question 17

Mepolizimab MOA

Answer 17

binds to IL-5 and prevents it from binding to its receptor

IL 5 receptor alpha subunit, on the surface of eosinophil white blood cells

Question 18

Azathiprine MOA

Answer 18

antagonist of purine metabolism, resulting in the inhibition of deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and protein synthesis

Question 19

Cause thrombocytopenia

Answer 19

Abciximab first, then Eptifibatide, Tirofiban

Question 20

Hx of osteosarcoma DONT USE

Answer 20

“Paratides”

Question 21

Hx of Esophageal disorders or Renal DONT USE

Answer 21

Alendronate, Risedronate, Ibaudronate, Zoledronic Acid

Question 22

What does Abciximab act on

Answer 22

GP 2B / 3A receptors

Question 23

Pregnant + thrombosis risk DONT USE

Answer 23

Warfarin (inhibit VKOR)

Question 24

LA contra for metformin

Answer 24

(bad kid/LD/alc/HF/inf)

Question 25

Hypoglycemia sx

Answer 25

(palp/tremor/sweat/anx/hunger/cns)