Reoviridae Flashcards
Which of the following are NOT characteristics of family Reoviridae?
A. Spherical, non-enveloped virions
B. Double-stranded segmented RNA genome, with number of segments ranging from 6-8
C. Reassortment can occur, and does so between members of the same genus or serogroup
D. The two important subfamilies of Reoviridae are Sedoreovirinae and Spinareovirinae.
B. Is incorrect- there are 10-12 segments!
6-8 was Orthomyxoviridae!
Which of the following is NOT true of Bluetongue Virus?
A. It is spread through direct contact and aerosols
B. It is a member of the genus Orbivirus, with 10 RNA segments.
C. Affects domestic and wild ruminants, with fine wool/mutton breeds of sheep of Europe and white-tailed deer being most susceptible.
D. Cattle are the primary reservoir and amplifying hosts
A. It is NOT contagious between animals but is transmitted through an insect vector, Culicoides spp
T/F:
Bluetongue Virus is a List A OIE virus, with high economic impact and rapid spread, and modes of transmission are biologically via Culicoides spp biting midges, transplacental and venereal routes.
True
When sheep go down on each other, their tongues turn blue! lol
Which of the following is INCORRECT regarding Bluetongue transmission and distribution in the U.S.?
A. In the U.S., the main vector is C. variipennis var sonorrensis
B. In the southeastern U.S., the main vector is C. insignis
C. Culicoides serve as mechanical vectors for the virus.
D. Serotypes 2, 10, 11, 13, and 17 are the most common in the U.S. and widely distributed throughout.
D.
10, 11, 13, 17- all over U.S.
2- Southeast mainly
Which of the following is NOT a clinical finding in Bluetongue virus?
A. Profuse salivation, with edema of muzzle
B. Mucopurulent nasal discharge, often bloody
C. Cyanosis, ulceration of tongue
D. Erosion of dental pad, oral lesions and crusts
E. Vesicles on coronary bands causing lameness
E.
There will be lameness, but caused by laminitis and coronitis NOT vesicles! No vesicles!
T/F:
African horse sickness can be passed to dogs if they eat infected carcasses, and it causes a fatal form of the disease.
True!!!
Which of the following is TRUE of African Horse sickness?
A. It is an Orbivirus transmitted by Culicoides, with a pathogenesis much like Bluetongue in sheep.
B. It is a OIE List A disease.
C. It infects many types of equids, but the zebra is the reservoir.
D. Several antigenic serotypes exist, and are classified in differences in outer capsid proteins VP2 and VP5
E. All are true
E. All true
T/F:
African Horse Sickness is enzootic in Northern Africa, the Middle East and Europe
False;
Enzootic in Sub-Saharan Africa
Occasional outbreaks have been reported in N. Africa, the Middle East and Europe
Which of the following are primary field vectors for African Horse Sickness:
A. C. variipennis var sonorrensis B. C. insignis C. C. imicola D. C. bolitinos E. A and B F. C and D.
F. C. imicola and C. bolitinos
Horses like cola and listening to Michael Bolton
but Sheep like drawing insignias on their penises
T/F:
Acute pulmonary form of African Horse Sickness is also called Dunkop and the Subacute form is called Dikkop
True
Dikkop (Subacute African Horse Sickness) is characterized by the following EXCEPT:
A. Hydropericardium and hydroperitoneum
B. Abdominal Serosal surface petechiae
C. Edema of muscles, eyelids, and supraorbital fossa
D. Petechiae of pulmonary pleura
D. pulmonary pleural petechiae is with the Dunkop (Acute) form
Dikkop= Serosal surface petechae in viscera, edema in viscera, muscles, eyelids, SO fossa, hydroperitoneum and hydropericardium
Dunkop= Petechiae on pulmonary pleura, foam in lungs and in trachea, FOAM from nares of dead horses!
T/F:
Rotavirus has 10 RNA segments, and classification is based on differences in VP6 protein into at least 8 groups designated as Rotavirus A-H.
False!
11 segments
The rest is true
T/F:
Rotavirus Group A is the most common cause of viral diarrhea for young animals of many species.
True!
T/F:
VP6, the major antigenic protein used to classify Rotaviruses, is an outer capsid protein.
False,
MIDDLE Layer protein (matrix protein???)
T/F:
The main site for replication of Rotavirus is the crypt cells of the villi of the upper small intestine.
False
Replicates in MATURE ENTEROCYTES!!!
Our professor is very mature and professional and he studies Rotavirus, so MATURE enterocytes
