Caliciviridae

Question 1

Which of the following is NOT a characteristic of Caliciviridae?

A. Non-enveloped virions that have 32 cup-shaped surface depressions.
B. Vesicular Exanthema of Swine is a disease caused by a virus in this family
C. It causes a very infectious disease in cats
D. Has linear, ss negative sense RNA
E. All of the above are true

Answer 1

D is NOT true— it has linear POSITIVE SS RNA, and therefore it serves as the mRNA and is infectious

I think of it as cups on the surface means I will probably put beer in those cups, which is a good thing…so its positive sense RNA

Question 2

Which of the following is NOT true of Feline Calicivirus?

A. It is in the genus Vesiculovirus
B. It typically causes mild oral and URI signs
C. Some strains cause lameness
D. Recently a virulent form, VSD, was discovered, which can cause fatal systemic infection.
E. All of the above are true

Answer 2

A.
VESIvirus is the genus within Caliciviridae
Vesiculovirus is a genus within Rhabdoviridae and causes Vesicular Stomatitis

He said he might just give virus etiologies and not names of diseases, so don’t mix those up incase he tries to trick us!!

Question 3

A cat comes into your clinic suffering from severe upper respiratory signs, ulcers on the tongue and oral mucosa, sloughing and hyperemia of the footpads, as well as fever, jaundice and anorexia and facial edema. The cat is up-to-date on its vaccines. The cat is most likely suffering from:

A. Feline Calicivirus (FCV)
B. FCV-VSD (systemic form)
C. Limping Syndrome caused by FCV
D. Feline Herpesvirus 1

Answer 3

B.

Question 4

T/F: Cats vaccinated for Calicivirus are not known to succumb to the highly virulent systemic form of the disease (VSD).

Answer 4

False!!

Question 5

T/F:
Vesicular Exanthema of swine is also a member of the genus Vesivirus, and its clinical signs are indistinguishable from Foot-and-Mouth Disease and Vesicular Stomatitis of pigs.

Answer 5

True