Paramyxoviridae Part II Flashcards
Choose the INCORRECT statement about peste de petits ruminants (PPR) virus: A. It is a morbillovirus, also known as Goat Plague B. It is grouped into 4 lineages based on the sequence of the F protein. C. It is more severe in goats, but can affect sheep. D. Adult goats and sheep can become persistent carriers of the virus if they recover.
D. There is NO carrier state in sheep or goats for this virus!
Which statement is TRUE regarding the lineages of PPR (goat plague)? A. Lineage 1 and 2 are present from the Middle East to Tibet B. Lineage 1 and 2 are present in West Africa C. Lineage 3 is present throughout Africa, the Middle East, and Tibet D. Lineage 4 extends from the Middle East to India
B. Lineage 1 and 2 are in East Africa is CORRECT Lineage 3 exists in Eastern Africa, the Middle East and Southern India Lineage 4 extends from the Middle East to Tibet
T or F: Although the mode of transmission is inhalation and it causes respiratory signs, Peste de Petits Ruminants Virus also causes gastrointestinal signs and animals may die of diarrhea and dehydration before respiratory signs become severe.
True!
Which of the following is the INCORRECT clinical finding for Peste de Petits Ruminants Virus? A. Lymphopenia B. Alimentary, respiratory and lymphoid mucosal erosions C. Severe respiratory distress D. Putrid breath E. Catarrhal conjunctivitis F. All of the above are clinical findings
F. All of the above
T or F: Early in the disease progression, animals with PPR (Goat Plague) will exhibit mucopurulent nasal discharge, which will progress to serous nasal discharge and cause a putrid odor to the breath.
False; it will start off serous and then progress to mucopurulent.
Which of the following viruses is MISMATCHED with its clinical sign: A. Newcastle Disease virus: torticollis B. Peste de petits ruminants virus: necrotic stomatitis C. Bovine Respiratory Syncytial Disease: Shipping Fever D. Rinderpest Virus: The “3 D’s”
C. Bovine Parainfluenza Virus 3 is the agent implicated in initiating Shipping Fever of Cattle, NOT BRSDV!
Zebra-striping of the large intestine is a hallmark finding on necropsy for which virus? A. Rinderpest Virus B. Newcastle Disease Virus C. Peste de Petits Ruminants Virus D. Akabane Virus
C.
Haha the goats look like little zebras!
What is the recommended diagnostic test for peste de petits ruminants virus?
A. PCR and immunofluorescence
B. ELISA
C. PPR-penside
D. Agar gel immunodiffusion assay
E. C and D
E.
PPR-penside and Agar gel immunodiffusion
***Goats DON’T look pensive but penside sounds like pensive, and goats like to diffuse to areas where you spilled your jell-o…goats will eat anything!
Which of the following diseases are reportable?
A. Newcastle Disease
B. Peste de petits Ruminants
C. Bovine Respiratory Syncytial Disease Virus
D. Bovine Parainfluenza Virus 3
E. A and B only
F. A, B, and C.
T or F:
Bovine Respiratory Syncytial Virus (BSRV) is classified into 2 antigenic subtypes based on differences in the F protein.
False!
The F protein was in Newcastle disease (F proteins were cleaved either intracellularly or extracellularly)
and in Peste de Petits Ruminants Virus (4 different lineages based on differences in the F protein)
Which of the following associations is UNTRUE regarding Bovine Respiratory Syncytial Virus?
A. More commonly seen in winter months
B. More common in cattle 6-12 months of age
C. The malignant form, Paroxystic Respiratory Distress syndrome, is associated with pulmonary mast cell degranulation
D. Pathogenesis of the fatal pneumonia caused by this virus is related to an IgE-mediated hypersensitivity reaction.
B.
More common in UNDER 6 months
T or F:
Bovine Respiratory Syncytial Virus is in the genus Pneumovirus and is characterized by syncytial cell bodies, intracytoplasmic inclusion bodies and hyaline membrane formation.
True!
T or F:
If calves recover from Bovine Respiratory Syncytial Virus, Disease, they will have life-long immunity.
False
Immunity is incomplete and short-lived.
A hallmark necropsy finding for Bovine Syncytial Virus is:
A. Marked distension and edema of lungs
B. Alveolar hyperinflation
C. Emphysema
D. Necrotic tracheobronchitis
E. All of the above except D
E.
