Renal Tubular Acidosis Flashcards
1
Q
What is the urine pH of distal RTA (type 1)?
A
> 5.5
2
Q
What is the urine pH of proximal RTA (type 2)?
A
<5.5
3
Q
What is the classical gas for RTA (both types)?
A
Non AG, hyperchloremic metabolic acidosis
4
Q
Which type of RTA is associated with hypercalciuria and nephrocalcinosis?
A
Type 1 Distal RTA
5
Q
Which type of RTA is associated with hyperkalemia?
A
Type IV RTA
6
Q
What is the mechanism for type IV RTA?
A
Hypoaldosteronism
7
Q
Which type of RTA is associated with hypocitraturia?
A
Type 1 Distal RTA
8
Q
What are some common types of Type 2 Proximal RTA?
A
- Fanconi syndrome
- Cystinosis
- Lowe syndrome
- Tyrosinemia type 1
- Galactosemia
- Wilson disease
9
Q
What are some common types of Type 1 Distal RTA?
A
- Marfan syndrome
- Wilson syndrome
- Ehler’s Danlos
- Familial hypercalciuria
- Medullary sponge kidneys
10
Q
What is the mechanism for Type 1 RTA (Distal)?
A
Increased H+ secretion –> NaHCO3 loss
11
Q
What is the mechanism for Type 2 RTA (Proximal)?
A
Decreased bicarbonate reabsorption
