Dermatology

Question 1

What are the clinical findings of incontinentia pigmenti?

Answer 1

1. Blistering rash in infancy
2. Wart-like skin growths with hyperpigmentation in swils in childhood
3. Hypopigmented lines in adults
4. Alopecia
5. Dental abnormalities
6. Eye abnormalities incld. vision loss
7. Pitted nails
8. Developmental delay and seizures?

Question 2

What is the advantage of benzoyl peroxide?

Answer 2

Decrease P acnes resistance to antibiotics

Question 3

What is Nikolsky’s sign?

Answer 3

Separation of areas of epidermis in response to gentle shear force
Seen in: SSSS and TEN

Question 4

What is urticaria pigmentosa?

Answer 4

Most common form of mastocytosis

Hyperpigmented lesions that become urticaria when stroked

Question 5

What topical agent can be used for atopic dermatitis?

Answer 5

First line: steroids

Second line: calcineurin inhibitor (tacrolimus)

Question 6

What is PHACE syndrome?

Answer 6

Posterior fossa malformations
Hemangiomas facial >5cm
Arterial anomalies
Coarctations of the aorta and other cardiac defects
Eye abnormalities (coloboma, etc.)
Sternal cleft