renal transporters Flashcards
1
Q
PCT
A
APICAL
- Na/H antiporter
- Na coupled cotransporter (AA/glucose)
- MDR transporter for cations
BASOLATERAL
- Na/K ATPase
- channels for AA/glucose
aquaporins
2
Q
descending loop
A
aquaporins only
3
Q
thin ascending loop
A
Na+ channels
Cl- channels
IMPERMEABLE to water
4
Q
thick ascending loop
A
APICAL
-NaK/2Cl cotransporter
BASOLATERAL
-Na/K ATPase
PARACELLULAR TRANSPORT (lumenal positive)
5
Q
DCT
A
APICAL
- Na/Cl cotransporter
- Ca channels
BASOLATERAL
- Na/K ATPase
- Ca ATPase
- Ca/3Na exchanger
6
Q
collecting duct (principal cells)
A
APICAL
- Na+ channel
- K+ channel
- aquaporin
BASOLATERAL
-Na/K ATPase
7
Q
collecting duct (a-intercalated cells)
A
carbonic anhydrase:
CO2 + H2O –> H+ (secreted apically) + HCO3- (reabsorbed basolaterally)
