Renal System Flashcards
Osmolarity
The concentration of solutes (salts, sugars, etc.) in a solution
Osmoconformers
Match their body osmolarity to the surrounding environment (most marine invertebrates, sharks)
Osmoregulators
Maintain a constant internal osmolarity regardless of the environment (most freshwater and terrestrial vertebrates)
Osmoregulatory Organs
Kidneys, gills, salt glands, and skin
Freshwater
Hypotonic environment where water enters body, salt out
Salt Water
Hypertonic environment where water leaves body, salt enter
Stenohyaline
Organisms that can only survive within a narrow range of salinity
Euryhaline
Organisms that can tolerate a wide range of salinities
Osmoregulating Hormones
Aldosterone, ADH, RAAS (Angiotensin), Cortisol, Renin
Water-Conserving Adaptations
Behaviors, Structures, Mechanism, Metabolic Water
Ammonotelic
Nitrogenous waste excreted as ammonia, most aquatic
Ureotelic
Nitrogenous waste is excreted as urea; most terrestrial and sharks
Uricotelic
Nitrogenous waste excreted as uric acid (birds, reptiles, desert animals, purine metabolism)
Glomerular Filtration Rate (GFR)
Amount of filtrate produced by kidneys each minute
NFP
NHP - COP
Glomerulus
Network of capillaries within the Bowman’s capsule, empty much of the fluid from the blood
Increased Aldosterone
Increased Sodium/Potassium Reabsorption
RASS Pathway
Stimulated by low blood pressure
Renin
Converts Angiotensinogen to ATI
ACE
AT1 to AT2
ADH (Vasopressin)
increased permeability of the collecting duct when dehydrated
Descending Loop of Henle
H2O leaves
Ascending Loop of Henle
Na+/K+/Cl- leaves
Urea
polar, can cross the membrane, can be reabsorbed
Distal Convoluted Tubule
Aldosterone Sensitive
Renal Threshold
Upper limit to reabsorption
Diabetes Mellitus
glucose will appear in the urine
Renin/Angiotensin
Increase BP
Mesangial Cells
Help control blood flow through the glomerulus, found between the capillaries
Podocytes
Issue several foot processes that form filtration slits, and interact with the basement membrane to create a filter that retains blood cells and large proteins in the plasma while permitting the passage of fluids through filtration slits
Angiotensin II (PG)
Vasopressin release
Angiotensin II (Adrenals)
Aldosterone release
Angiotensin II (Arterioles)
Vasoconstriction
Blood volume increase, resistance increase
Increased BP
ADH Pathway
Binds to G-coupled protein, triggers Protein Kinase A, cytoskeleton translocates aquaporins to cell surface for increased permeability