Hormones Part 2 Flashcards
EPO
Produced in the Kidney, Upregulates RBC production and targets bone marrow
Vit B
Produced in the Kidney, Upregulates Ca+ levels and effects bones, urine, and digestive system
GHRH -> GH
Second Order Feedback
TRH -> TSH -> T3/T4
Third Order Feedback
Infundibulum
Connects the hypothalamus to the pituitary gland
Posterior Pituitary Gland
ADH/Oxytocin
Positive Feedback Loop
Oxytocin, Prolactin
Pars Distalis
Anterior Pituitary
Pars Nervosa
Posterior Pituitary
Pars Intermedia
Melanocyte
Tropic Effects Only (Gland)
FSH, LH, TSH, ACTH
Non-tropic Effects Only (Organ)
Prolactin, MSH
Tropic and Non-tropic Effects
GH
FSH/LH Target
Testes/Ovaries
TSH Target
Thyroid
ACTH Target
Adrenal Cortex
Prolactin Target
Mammary Glands
MSH Target
Melanocytes
GH Target
Liver, bones, other tissues
Stress
Upregulates ACTH/Cortisol
Phase 1: Alarm
Sweat, Increase Heart Rate and Breathing
Phase 2: Resistance
Mobilized energy, health problems (muscle atrophy)
Phase 3: Exhaustion
Liver reserves empty, organ failure, collapse of vitals, no electrolyte balance
Sympathetic
Fight/Flight
Parasympathetic
Rest/Digest
Short-term stress response
Increased BP/breathing/metabolic rate, increased alertness, decreased digestive
Long-term stress response
Increased BP, Sodium retention, Immune suppression, protein and fats broken down
Glucocorticoids
Sugar derived, corticosterone, cortisol
HPA
Hypothalamic-Pituitary-Adrenal Axis, 3rd Order
Midsagittal View
Separates into two mirror images, midline
Coronal Cut
Front Plane
Dorsal
Back
Anterior
Head
Ventral
Front
Superficial
Closer to outside
Deep
Closer to inside
Posterior
Tail
Distal
Further Appendage
Proximal
Closer Appendage
Inferior View
Bottom
Superior View
Top
Mammillary Bodies
Motivation, Emotion, Learning, and Memory
Thalamus
Gateway to the brain determines what sensory information goes to cortex
Epithalamus
Dark region with pineal gland which secretes melatonin
Thyroid
2 lobbed gland with follicular and parafollicular cells
Follicular Cells
Make thyroid hormone T3.T4 (Metabolic), Iodide
Parafollicular Cells
Make calcitonin, decrease blood calcium levels (C cells)
Adrenal Cortex
G (Aldosterone), F (Cortisol), R (Androgen)
Adrenal Medulla
Norepinephrine, Epinephrine
Vasomotion
Vasodilation (Heart, Respiratory, Skeletal Muscle)
Retroperitoneal
Kidneys are behind the abdominal cavity
Pancreas Islets
Alpha (glucagon), Beta (insulin), Delta (somatostatin)
Acinar Cells (Pancreas)
Make alkaline juice to neutralize stomach acid, make digestive enzymes to digest lipids, carbs, and proteins