Renal: Reabsorption, Secretion, Excretion

Question 1

where is most of the reabsorption taking place in the kidneys?

Answer 1

proximal tubule

Question 2

what happens in the descending limb of the loop of Henle?

Answer 2

permeable to water only, no reabsorption of ions

Question 3

what happens in the ascending limb of the loop of Henle?

Answer 3

permeable to ion reabsorption, but not water

Question 4

what is the sodium/potassium/chloride transporter and where does it work?

Answer 4

reabsorbs sodium, potassium, and chloride in the ascending loop of Henle

Question 5

what is the effect on of NKCC on fluid volume and BP?

Answer 5

more ions being reabsorbed means more water being pulled, which increases BP

Question 6

what is the responsibility of the distal tubule?

Answer 6

fine tuning – reabsorbed or secretes whatever needs to be done

Question 7

what is the role of aldosterone in the distal tubule?

Answer 7

increases BP by reabsorbing Na+ out of the tubule

Question 8

what effect does ADH have on the collecting duct?

Answer 8

ADH increases water reabsorption in the collecting duct, increasing BP

Question 9

how does cell lysis affect potassium levels?

Answer 9

increases K+ in the blood

Question 10

what affect does insulin have on potassium levels?

Answer 10

insulin decreases K+ in the blood

Question 11

what is creatinine and why is it relevant to monitoring GFR and kidney function?

Answer 11

not reabsorbed which means it is 100% excreted
high creatinine = poor kidney function