Renal Disease Flashcards
Function of the kidneys?
Production of blood
Production of urine
Hormone synthesis
Reabsorption of water
Blood in the urine?
Damage
Dipstick testing
Easy to use
Urea
Synthesised in the liver
By product of deamination of amino acids
Diffuse freely through membranes
Urea levels can be affected in a number of situations
What is Creatinine?
By product of muscle metabolism
The ranges of urea?
2.5-8 mmol/L
The functional unit in the kidney?
The Nephron
What is the glomerular function?
Fluid maintenance
Electrolyte & pH balance
What affects the glomerulus?
Blood pressure
Number and area covered by nephrons
Estimation of the glomerular filtration rate?
GFR
Accepted as the best overall measure of kidney function
A decrease in GFR—>renal failure
Used to monitor progression
How do you calculate GFR?
GFR x (PS) = (US) x V
Then
GFR= (US)x V/ (PS)
Proteineria is an indicator of what?
Glomerular function
They indicate damage to the basement membrane