Renal Disease 2 Flashcards
What causes AKI?
By rising serum urea and creatinine
Pre renal causes of AKI?
Vomiting
Loss of blood
Sepsis
Post renal causes of AKI?
Bladder prostate and cervical cancer
Renal stones
Intrinsic renal disease
Glomerular disease
Micro vascular disease
What aids diagnosis?
Patient history
Lab tests
Acute tubular necrosis (ATN)
What’s the cause of ATN?
Causes by ischamic or nephrotoxic injury to the kidney
Management of the disease?
Biochemical analysis
Treatment of the underlying disease
What’s chronic kidney disease?
Progressive irreversible destruction of kidney tissue for atleast 3 months
Origin of chronic kidney disease?
Hypertension
Lupus
Diabetes
Why does chronic kidney disease occur?
Due to the loss of functioning nephrons
What’s uraemia?
The terminal clinical manifestation of kidney failure
Management of CKD?
Conservative measures to alleviate symptoms
Patients monitored by biochemical testing
What’s proteinuria
Classic sign of renal disease
Used for diagnosis and prognosis
The presence and excess of serum proteins in the urine
What’s nephrotic syndrome?
Non specific kidney dosorder Characterised by 3 signs of disease: 1-large proteinuria 2-hypoalbumin 3-edema--->swelling
Loss of glomerular proteinuria leads to…
Inflammatory reactions
Activation of the complement pathway
Release of anaphylatoxic components
